T�tulo: Design & Evaluation of Controlled Release Matrix Tablets of Prazosin: Modern Management of Hypertension
Editor: LAP LAMBERT Academic Publishing
Fecha de publicaci�n: 2018
Idioma: Ingl�s
ISBN 10: 6138387821
ISBN 13: 9786138387824
Encuadernaci�n: Paperback
Estado: Brand New

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Sinopsis

In the present study, we have prepared matrix tablet formulations using Prazocin as a model drug and Ethyl Cellulose, Two grades of Hydroxy Propyl Methyl Cellulose- HPMC-K4M & HPMC-K100M as polymers in different ratios. The developed matrix tablets were evaluated for different physical-chemical evaluations like drug content, hardness, friability, swelling index etc. All the formulations had shown the results within prescribed limits. The In vitro drug release study indicates that formulation PCF-7 containing EC, HPMC K100M in 1:2 ratio shown good release pattern for 14 hours compares to other formulations. The short-term stability study proved no change in the formulation of ageing and it indicates good stability.

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Edward Bowditch Ltd
Exstowe, Exton, Exeter, EX3 0PP, United Kingdom

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Legal entity name: Edward Bowditch Ltd
Legal entity form: Limited company
Business correspondence address: Exstowe, Exton, Exeter, EX3 0PP
Company registration number: 04916632
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Authorised representative: Mr. E. Bowditch