Colon-Targeted Therapies Using Co-Amorphous Systems (Paperback)

Idioma: inglés

Editorial: Eliva Press, 2025

9999328881 / 9789999328883

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Librería: CitiRetail, Stevenage, Reino UnidoCitiRetail

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Paperback. The colon has emerged as a critical target site for the delivery of therapeutic agents, not only for the local treatment of diseases such as ulcerative colitis, Crohn's disease, and colorectal cancer but also for the systemic delivery of peptides, proteins, and other drugs that degrade in the upper gastrointestinal (GI) tract. As challenges persist in achieving site-specific delivery and ensuring drug stability and bioavailability in the dynamic environment of the GI tract, the development of novel formulation strategies is of paramount importance. Co-Amorphous Pellets for Colon Targeted Delivery presents a timely and comprehensive exploration of a promising formulation approach at the intersection of material science, pharmaceutics, and drug delivery technology. This book delves deeply into the innovative use of co-amorphous drug systems, a relatively new but rapidly advancing field formulated into pelletised dosage forms designed specifically for colon-targeted delivery. Co-amorphous systems, in which an active pharmaceutical ingredient (API) is stabilised in its amorphous form via molecular interactions with a small molecule co-former, offer a powerful alternative to traditional solid dispersions or crystalline drug forms. By preventing recrystallisation and improving drug solubility and dissolution rates, co-amorphous systems can dramatically enhance the therapeutic performance of poorly water-soluble drugs. In a time when personalised and targeted drug delivery is gaining increasing importance, this book contributes to a deeper understanding of co-amorphous systems and their vast potential in addressing solubility and targeting challenges. It provides a strong foundation and practical guidance for developing next-generation colon-targeted therapies using co-amorphous pellet formulations. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. …

N° de ref. del artículo 9789999328883

Título
Colon-Targeted Therapies Using Co-Amorphous Systems (Paperback)
Autor
Ajay Ashok Bhagwat
Editorial
Eliva Press
Año de publicación
2025
Estado
new
Encuadernación
Paperback
Idioma
inglés
ISBN 10
9999328881
ISBN 13
9789999328883

CitiRetail

Stevenage, Reino Unido

Vendedor de 5 estrellas

Vendedor de IberLibro desde 29 de junio de 2022

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ArtículoDe 7 a 14 días hábilesDe 7 a 60 días hábiles
Primer artículoEUR 44,18EUR 44,18
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