Codon Evolution (Hardcover)

Idioma: inglés

Editorial: Oxford University Press, Oxford, 2012

019960116X / 9780199601165

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Hardcover. Codon-based models of evolution are a relatively new addition to the toolkit of computational biologists, and in recent years remarkable progress has been made in this area. The study of evolution at the codon level captures information contained in both amino acid and synonymous DNA substitutions. By combining these two types of information, codon analyses are more powerful than those of either amino acid or DNA evolution alone. This is a clear benefit for mostevolutionary analyses, including phylogenetic reconstruction, detection of selection, ancestral sequence reconstruction, and alignment of coding DNA. Despite the theoretical advantages of codon basedmodels, their relative complexity delayed their widespread use. Only in recent years, when large-scale sequencing projects produced sufficient genomic data and computational power increased, did their usage become more common.In Codon Evolution, leading researchers in the field of molecular evolution provide the latest insights from codon-based analyses of genetic sequences. The first part of the book provides comprehensive coverage of the developments of varioustypes of codon substitution models such as parametric and empirical models used in maximum likelihood as well as Bayesian frameworks. Subsequent chapters examine the use of codon models to infer selection andother applications of codon models to biological systems. The second part of the book focuses on codon usage bias. Both the underlying mechanisms as well as current methods to analyse codon usage bias are presented. The the first authoritative and up-to-date review of evolution at the codon level, investigating the mechanisms and particularities of coding regions using the latest statistical analyses and codon-based models of evolution. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.…

N° de ref. del artículo 9780199601165

Título
Codon Evolution (Hardcover)
Autor
Gina M. Cannarozzi
Editorial
Oxford University Press, Oxford
Año de publicación
2012
Estado
new
Encuadernación
Hardcover
Idioma
inglés
ISBN 10
019960116X
ISBN 13
9780199601165

CitiRetail

Stevenage, Reino Unido

Vendedor de 5 estrellas

Vendedor de IberLibro desde 29 de junio de 2022

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