Clinical Nephrotoxins. Este artículo no está disponible.Clinical Nephrotoxins

To you the reader, the joy of discovery begins, for We continue in our goal of providing a text which us the job is done. In this edition, we have corrected is useful, not only to the clinician, but of equal interest past deficiencies, added new topics, expanded infor- to the investigator. The selection of content has been mation regarding the pediatric age group, provided directed at topics of current interest rather than those up to date (March 2003) references, while remaining of historic contribution. We have stressed the cont- true to our concept of a multi-national author book. bution of cell biology and pathophysiology, were it We continue to believe that scientific information is an exists, believing it provides both a better understa- international commodity whose interpretation and ap- ing of toxic injury when known, and a rational dir- plication are strongly influenced by both the cultural tion for therapy and prevention. and ethnic background of the observer. The oppor- nity to share in the rich diversity of the international We are encouraged by the accumulation of rec- scientific community remains a fundamental goal of nized risk factors, which allow pre-treatment strati- this endeavor. To participate as equals leads to mu- cation of our patients’ relative risk and allow us to - tual respect and peer appreciation. The sharing of in- cus our preventative techniques on the individuals tellectual resources fostered by this effort should and most likely to gain the greatest benefit.

"The first section, on general matters, contains the best short account of "renal handling of drugs and xenobiotics" that I have seen. One chapter is a thorough account of urinary biomarkers that would be worthwhile reading for anyone contemplating a clinical study and wanting information on what might be measured to indicate nephrotoxicity. In summary, the books contains some splendid articles on nephrotoxicity and nephrotoxins, from a scientific perspective [...] this could become a comprehensive and standard text."
(John Firth in The Lancet, January 2004)