Brain Tumors : Advancements in Diagnostics and Innovative Therapies

This book offers a comprehensive exploration of brain tumors, beginning with a foundational understanding of their pathophysiology and extending through the latest advancements in diagnosis and treatment. The chapters examine the underlying mechanisms that drive the development and progression of brain tumors and present a detailed analysis of the incidence, distribution, and potential risk factors associated with brain tumors. The book explores the intricate relationship between brain tumors and visual disorders, and reviews the critical role of advanced imaging technologies in diagnosing brain tumors, evaluating the strengths and limitations of various modalities such as MRI and PET scans. Additionally, the book evaluates the effectiveness and precision of radiosurgery in targeting brain tumors, discussing its benefits and challenges in the context of non-invasive cancer treatment. The chapters also introduce us to antisense oligonucleotides as a novel therapeutic strategy, outlining their mechanism of action and potential to silence cancer-driving genes. The book highlights the latest developments in nanotechnology for brain tumor diagnosis, emphasizing the use of nanomaterials to enhance imaging quality and specificity.

Key Features:

• Provides a thorough exploration of brain tumors, from basic pathophysiology to advanced treatment options
• Presents detailed analyses of the incidence, distribution, and potential risk factors associated with brain tumors
• Discusses the critical role of imaging technologies, including MRI and PET scans, in the diagnosis of brain tumors
• Introduces novel therapeutic strategies such as radiosurgery and antisense oligonucleotides for targeting brain tumors
• Examines strategies to overcome the blood–brain barrier for effective drug delivery

Toward the end, the book covers challenges of and strategies for delivering therapeutic agents across the blood–brain barrier and discusses phytochemicals in brain tumor treatment. This book serves as a useful source for researchers and students in oncology and neuroscience.

Dr. Xiaodong Li is a Chief Physician at Shengjing Hospital of China Medical University, 36 Sanhao St, Heping District, Shenyang, Liaoning, China with an MDPHD in neurosurgery. With over 13 years of experience and having completed more than 1,500 neurosurgical operations, Dr. Li specializes in epilepsy surgery and cerebrovascular disease, demonstrating profound expertise in cerebral vascular bypass surgery and the treatment of cerebral aneurysms, among other conditions.

Dr. Yawen Ma, also a Chief Physician and Neurosurgeon at Shengjing Hospital of China Medical University, 36 Sanhao St, Heping District, Shenyang, Liaoning, China, holds an MDPHD. Dr. Ma has a distinguished background in treating intracranial diseases, including tumors and vascular diseases, since 2017.

Dr. Zirong Fan is working as a Lecturer and Researcher at Shengjing Hospital of China Medical University, 36 Sanhao St, Heping District, Shenyang, Liaoning, China and holds an MDPHD in neurosurgery. Graduating in 2020, Dr. Fan is working towards understanding the molecular mechanism of brain tumors and innovative strategies for diagnosis and treatment of brain tumors.

Dr. Rekha Khandia serves as an Assistant Professor in the Department of Biochemistry and Genetics at Barkatullah Vishwavidyalaya, Bhopal, Hoshangabad Road, Bhopal, Madhya Pradesh, India. Dr. Khandia's work stands at the intersection of molecular diagnostics, vaccine development, neurosciences, brain tumors, and the study of infectious diseases through the lens of genetics and biochemistry. She has published more than 100 research articles in respected journals and authored two books. She is also actively involved in reviewing high-impact journals and participating in various academic forums.