Biological Time Control (Hardcover)

Idioma: inglés

Editorial: Springer Nature Switzerland AG, Cham, 2026

3032361885 / 9783032361882

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Hardcover. How do cells keep time? For decades, biological timekeeping has been understood through the lens of master clocks: the CDKCyclin oscillator that drives the cell division cycle and the circadian clock that aligns physiology with the daynight cycle. Yet recent discoveries are reshaping this view. Cellular time control is now emerging as a phenomenon governed not solely by such master clocks, but by coupled networks of otherwise independent timing mechanisms dedicated to specific cellular events.This book introduces and defines the emerging concept of autonomous clocks: cellular timing systems that can be entrained by canonical cell-cycle or circadian programs, yet retain the ability to operate independently to time and execute specific biological events. These autonomous clocks are increasingly recognized across organelle biogenesis, transcription, cytoskeletal remodeling, redox metabolism, proteostasis, immunity, nuclear organization, and even cytoplasmic division independent of nuclei and classical cell-cycle control. Together, they reveal a rich temporal architecture of the cellone in which subcellular processes are not merely passive outputs of master clocks but are governed by dedicated oscillators that act as autonomous timing systems.Bringing together leading voices in cell biology, physiology, synthetic biology, biophysics, and mathematical biology, this volume offers the first comprehensive account of autonomous clocks as a unifying framework for biological time control. The chapters span foundational discoveries in autonomous transcriptional, cytoskeletal, redox, proteostasis, immune, and otherwise sub-cellular timing systems, while also exploring how these autonomous cycles couple to broader cellular rhythms, how they may be engineered synthetically, and how their principles can be understood through theory and computation. By synthesizing a decade of rapidly expanding discoveries, this book challenges long-standing textbook models of cellular timekeeping and opens new conceptual ground for understanding how cells coordinate physiology, maintain temporal order, and preserve function when canonical clocks are slowed, suspended, or silenced.Biological Time Control: Autonomous Clocks in Cellular Organization, Dynamics, and Function is an essential resource for students, researchers, and scholars interested in biological time control from the perspective of cell biology, systems biology, synthetic biology, physiology, and the molecular logic of cellular organization. It will be especially valuable to readers seeking a forward-looking framework for how timing mechanisms shape life at the subcellular, cellular, and organismal scales. Cellular time control is now emerging as a phenomenon governed not solely by such master clocks, but by coupled networks of otherwise independent timing mechanisms dedicated to specific cellular events. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.…

N° de ref. del artículo 9783032361882

Título
Biological Time Control (Hardcover)
Autor
Mustafa G. Aydogan
Editorial
Springer Nature Switzerland AG, Cham
Año de publicación
2026
Estado
new
Encuadernación
Hardcover
Idioma
inglés
ISBN 10
3032361885
ISBN 13
9783032361882

CitiRetail

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