This book provides practical knowledge to biomedical researchers using biological and biochemical specimen in order to understand health and disease processes at cellular, clinical, and population levels. Concepts and techniques provided will help researchers design and conduct studies, then translate data from bench to clinics.

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Laurens Holmes Jr. was trained in internal medicine, specializing in immunology and infectious diseases prior to his expertise in epidemiology (cancer)-with- biostatistics (survival analysis). Over the past two decades, Dr. Holmes had been working in cancer epidemiology, control & prevention. His involvement in biostatistical modeling of health research data includes signal amplification and stratification in risk modelling, evidence discovery through effect size and confidence interval (not p value) and evidence-based clinical and translational research through Quantitative Evidence Synthesis (QES).

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