Alternative Approaches to Human Blood Resources in Clinical Practice

Idioma: inglés

Editorial: Springer, Springer Okt 2012, 2012

1461375711 / 9781461375715

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This item is printed on demand - Print on Demand Titel. Neuware -Currently blood is a volatile issue. The safety of blood and the quantification of transfusion risks have been dominant themes that have stimulated the development of alternative approaches in this rapidly developing area. In clinical medicine conventional blood and its components are used in supportive therapies dependent on the choice of apparent uncritical trigger factors. A compounding factor is depth of prospective clinical trials for evidence. Such trials in critical care areas would be of enormous value, not only in recording adverse effects and under-transfusion, but also indicating the value of decision analysis and cost-effectiveness in transfusion practice. Alternative approaches include the use of cytokines, growth factors, humanised monoclonal antibodies, recombinant plasma factors, and buffy coat derived natural human interferons. These are being increasingly implemented in the clinic. Solutions for oxygen transport are being developed and fibrinogen coated microcapsules are being investigated for thrombocytopenia. In surgical patients, various crystalloid and colloid combinations are explored as volume replacements. To avoid allogeneic transfusions, beneficial blood saving methods include various strategies, such as autologous deposits, normovolemic haemodilution and various agents including aprotinin, tranecamic acid, desmopressin and erythropoietin, but their use in hospital shows considerable variations. That umbilical cord blood could be a significant source of allogeneic stem cells in related and unrelated transplantation is illustrated by the increasing number of cord blood banks in Europe and elsewhere. Future blood resources are likely to face several challenges: immediate challenges relate to increased regulatory and political oversights; intermediate solutions would offer some improvements in public health and alleviate public fear but probably not address the economic challenges thrust upon the medical care system.As we approach the year 2000, the major concerns about transfusion medicine remain its logistics, safety and effectiveness. This theme is presented in the proceedings of the 22nd International Symposium on Blood Transfusion, developed in 21 up-to-date topics, collected and discussed in four sections.This book will be of timely value to students, professionals and all others interested or involved in the field of transfusion medicine, whether clinical or related.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 280 pp. Englisch.

N° de ref. del artículo 9781461375715

Título
Alternative Approaches to Human Blood Resources in Clinical Practice
Autor
C. Th. Smit Sibinga
Editorial
Springer, Springer Okt 2012
Año de publicación
2012
Estado
Neu
Encuadernación
Taschenbuch
Idioma
inglés
ISBN 10
1461375711
ISBN 13
9781461375715
Peso del artículo
452 gramos
Dimensiones
240x160x16 mm

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