Advanced Manufacturing Technologies in Biomedical Science: Practical Applications, Case Studies, and Future Trends

As healthcare challenges such as human aging and traffic accidents continue to increase exponentially, the biomedical sector faces a significant obstacle in arranging patient-specific biomedical products. Over the past two decades, additive manufacturing’s printing quality and ease of production have gained global attention, particularly in the development of scaffolds and implants.

This book explores additive manufacturing technologies and their categorization, materials, processing factors, output responses, advantages, challenges, and biomedical applications. It provides a critical analysis of past biomedical applications of additive manufacturing technology, explores recent advancements, and examines the design, applications, and characterizations of biomedical components using additive manufacturing techniques. Moreover, it discusses notable applications of additive fabrication in aerospace, education, and medicine, as it showcases the medical applications of rapid prototyping, addressing computational and experimental aspects of 3D-printed biomedical devices. Also, it provides future human implications and developments.

Advanced Manufacturing Technologies in Biomedical Science: Practical Applications, Case Studies, and Future Trends offers a unique framework for understanding and evaluating the latest advancements in biomedical additive manufacturing. This book targets individuals interested in conducting research, providing valuable insights, and can serve as an authoritative source of information for manufacturers and academic researchers in the business sector.

Dr. Jashanpreet Singh is currently working as Assistant Professor in ‘University Center for Research and Development’ at Chandigarh University, Mohali, Punjab, India. He obtained his PhD in the field of slurry erosion and thermal spray coatings from Thapar Institute of Engineering and Technology, Patiala, India, in 2019. He has teaching experience of more than five years and industry experience of more than two years. His areas of research include tribology-solid particle erosion, power plant engineering, ash conveying, thermal spray coatings, CFD simulation, composites, and material characterization. He has contributed comprehensively on thermal spray coatings and tribology in reputed journals including Wear, Tribology International, Ceramics International, Applied Surface Science Advances, Particulate Science and Technology, Engineering Failure Analysis, ASME: Journal of Tribology, ASCE Journal of Pipeline Systems―Engineering and Practice, Coatings, Proceedings of IMeche Part J: Journal of Engineering Tribology, Part E: Journal of Process Mechanical Engineering, Surface Review and Letters, Materials Science and Engineering B, and Industrial Lubrication and Tribology, under the flagship of various publishers. He has authored 85+ research publications in which 52 publications are indexed in SCIE/ESCI (Web of Science) and 76 are indexed in Scopus database in various international journals, books, and conferences of repute. He has authored a book with CRC Press and chapters in six different CRC Press books. He is a reviewer for various journals such as Ceramics International, Surface Coatings and Technology, Tribology in Industry, Surface Topography: Metrology and Properties, Vacuum, IMeche Part E: Journal of Process Mechanical Engineering, Material Research Express, Surface Review and Letters, International Journal of Interactive Design and Manufacturing, Industrial Lubrication and Tribology, and Materials Today: Proceedings. He serves as a guest editor or section editor on numerous scientific journals. He is listed in World’s Top 2% Scientists by Stanford University from 2022 to 2024. He has received "Trusted Reviewer Status" from the Institute of Physics (IOP) in 2020. He has been awarded the "Outstanding Reviewer Award 2021" by the Institute of Physics (IOP) for the journal Surface Topography: Metrology and Properties. He is a life member of AICTSD, IAENG, and NITTSD.

Dr. Hitesh Vasudev is working as Professor in the School of Mechanical Engineering, Lovely Professional University, Phagwara, Punjab, India. He received his PhD from Guru Nanak Dev Engineering College, Ludhiana, Punjab, India, in 2018, under the guidance of Prof. (Dr.) Harmeet Singh, GNDEC, Ludhiana, and Dr. Lalit Thakur, NIT, Kurukshetra. His research areas include surface engineering/thermal spraying (HVOF, flame spray, cold and plasma spray, and microwave claddings). He is currently working on the development of nanostructured, multi-modal, and high-entropy alloy coatings for high-temperature oxidation- and corrosion-resistance thermal barrier coatings (TBCs) and microwave processing of materials. Recently, he has been listed in World’s Top 2% Scientists published by Stanford University and Elsevier (2023 and 2024). He has contributed extensively on thermal spray coatings in reputable journals, which include Surface Coatings and Technology, Materials Today Communications, Engineering Failure Analysis, Journal of Cleaner Production, Surface Topography: Metrology and Properties, Journal of Failure Analysis and Prevention, International Journal of Surface Engineering, and Interdisciplinary Materials Science, under the flagship of various publication groups. Moreover, he is a dedicated reviewer of reputed journals such as Surface Coatings and Technology, Journal of Thermal Spray and Technology, Ceramics International, Journal of Material Engineering Performance, Engineering Failure Analysis, Surface Topography: Metrology and Properties, Material Research Express, Engineering Research Express, and IGI Global journals. He has been awarded "Top Cited Paper Awards India 2022" by IOP Publishing, the UK, in Review Category. He has won Research Excellence Award in 2019, 2020, 2021, and 2023 from Lovely Professional University, India. He has 40+ SCI-indexed papers, 100 Scopus-indexed papers, 15 conference papers, 5 books (1 self-authored and 4 edited books), and 25 book chapters. He has been granted a patent titled "High-Temperature Oxidation and Erosion Resistant Alloy-718/Al2O3 Composite Coatings." He has organized one national conference and many international conferences. He has received seed money for a project tilted "Fabrication of Coatings for Bio-Medical Applications," Project Number: LPU/DRD/SEED/SAC/140222/24804, from Lovely Professional University. He has received a grant from Scientific Engineering and Research Board (SERB), New Delhi, Government of India, to conduct a conference in 2023.

Prof. Chander Prakash is Group Pro-Vice Chancellor of Rayat Bahra University, Mohali, Punjab, India. He is an accomplished academic leader with over 18 years of extensive experience in academic administration, research, and global university rankings. A visionary professional, he has driven transformative initiatives in higher education, focusing on elevating institutional reputation and cultivating a thriving research ecosystem. He is a passionate researcher with diversified research interests such as developing materials for biomedical and healthcare applications and additive manufacturing and developing and exploring new cost-effective manufacturing technologies for biomedical industries. He has published over 397 (326 SCI/Scopus) scientific articles in peer-reviewed, reputable, top-notch journals, conferences, and books. Dr. Prakash is a highly cited researcher at the international level, with 8,010 citations, an H-index of 50, and an i-10 index of 173. He is among India’s Top 1% of leading mechanical and aerospace engineering scientists, as per Research.com. He holds the 38th rank in India and 1,590th rank in the world. He also consistently appeared in the top 2% of researchers as per Stanford Study in 2021, 2022, 2023, and 2024. As a prolific author, Prof. Prakash has edited or authored 35 books, served as Series Editor for 3 book series, and contributed as Guest Editor for leading journals. He currently serves as the Editor-in-Chief of prestigious international journal IECE Transactions on Advanced Functional Materials and Processing. He is also an editorial board member of highly reputed journals. Beyond publications, Prof. Prakash has significantly contributed to Intellectual Property Rights (IPR), with 18 patents filed, 6 granted, and has successfully raised $1.2 million in research grants from bodies like DSTSERB, UKIERI-DST, and the Ministry of Science and Technology, Government of India. His outstanding contributions have earned him the Research Excellence Award (2019, 2020, 2021). He has actively contributed to institutional accreditation as an NAAC Assessor and Chairperson, ensuring academic quality and excellence.

Dr. Manpreet Singh is Computational Research Scientist at the Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, Maryland, USA, in support of the Department of Defense Biotechnology High Performance Computing Software Applications Institute (DOD-BHSAI), Telemedicine and Advanced Technology Research Center (TATRC), United States Army Medical Research and Development Command (USAMRDC), Fort Detrick, Maryland, USA. Dr. Singh received his PhD in mechanical engineering (thermo-fluids sciences specialization) from the University of Maryland. During his PhD, Dr. Singh worked on a National Science Foundation (NSF-1705538)-funded project titled "Mild Hyperthermia to Enhance Delivery of Therapeutic Nanocarriers in Tumors: Imaging, In Vivo Study, and Simulation." He is one of the few leading interdisciplinary experts in the fields of thermal engineering and mathematics and is well known for developing mathematical models of biological systems and medical devices to identify novel diagnostic and treatment strategies to improve the care available for chronic diseases, such as cancer and type-1 diabetes, and cold-related injuries, such as frostbite and loss of dexterity, hypothermia, and so on. Most importantly, Dr. Singh’s work in developing novel medical devices is exemplary, as the multi-orifice insulin delivery device that he developed is currently undergoing human clinical trials in the United States and Europe to obtain Food and Drug Administration 510K approval and CE Mark approval. His multi-hole cannula design being commercialized for insulin delivery demonstrates the impact of Dr. Singh’s work. Moreover, his open-source algorithm for magnetic coil design has been consistently adopted by other researchers to inform their own work. In addition, he has actively engaged his peers in the field of thermal engineering by authoring and coauthoring 35 peer-reviewed scientific publications, including 8 peer-reviewed journal articles, 2 peer-reviewed conference proceedings articles, 3 book chapters, and 22 peer-reviewed conference abstracts that have been published in leading international research journals such as International Journal of Heat and Mass Transfer, International Communications in Heat and Mass Transfer, ASME Journal of Heat Transfer, Computers in Biology and Medicine, and International Journal of Thermal Sciences. More recently, he has received early career recognition with the "AMMCS-2023 Kolmogorov-Wiener Young Researcher Award" at the VIth International Conference on Applied Mathematics, Modeling and Computational Science held at Wilfrid Laurier University, Waterloo, Ontario, Canada, from August 14 to 18, 2023, for improving the prominent mathematical model (Pennes Bioheat Transfer Equation 1948) to predict temperature distribution in cancerous tissues. Dr. Singh has studied the heterogeneous blood perfusion using medical imaging at each pixel location to relax the uniform blood perfusion assumption. Additionally, Dr. Singh is a recipient of three more research awards during his doctoral degree program at the University of Maryland, including the "Dissertation Fellowship Award," "Student Researcher of the Quarter Award," and "Graduate Student of the Month Award," and three times "GSA Professional Development Grantee." Such awards hold higher recognition as these awards were received from an "R1" doctoral university, classified as Research Extensive or Very High Research Activity (VHRA) university under Carnegie Classification of Institutions of Higher Recognition in the United States. Furthermore, Dr. Singh’s appointment as an academic editor for PLOS One, Guest Associate Editor for Frontiers in Thermal Engineering, Co-Guest Editor for Bioengineering and moreover, unsolicited invitations to review book proposals as a subject matter expert for Taylor & Francis Group, Judge for Senior Capstone Projects and International Conferences such as 10th American Society of Thermal and Fluids Engineering Conference, Topic Coordinator for Specialized research topics, review invitations for international journals such as Case Studies in Thermal Engineering, Thermal Science and Engineering Progress, Heat and Mass Transfer, Frontiers in Oncology, and many more topical advisor positions for journals testify to his high stature in the field of computational heat and mass transfer and mathematics.