Advanced Biosensors for Virus Detection: Smart Diagnostics to Combat SARS-CoV-2

Advanced Biosensors for Virus Detection: Smart Diagnostics to Combat Against the SARS-CoV2 Pandemic covers the development of biosensor-based approaches for the diagnosis and prognosis of viral infections, specifically coronaviruses. The book discusses wide-ranging topics of available biosensor-based technologies and their application for early viral detection. Sections cover the emergence of SARS-CoV, MERS-CoV and SARS-CoV2, the global health response, the impact on affected populations, state-of-the art biomarkers, and risk factors. Specific focus is given to COVID-19, with coverage of genomic profiling, strain variation and the pathogenesis of SARS-CoV2.

In addition, current therapeutics, nano-abled advancements and challenges in the detection of SARS-CoV2 and COVID-19 management are discussed, along with the role of nanomaterials in the development of biosensors and how biosensors can be scaled up for clinical applications and commercialization.

• Deals with biosensors-based approaches that could be exploited to design and develop high throughput, rapid and cost-effective diagnostics technologies for the early detection of viral infections
• Illustrates the development of multiplexed, miniaturized analytical systems for point-of-care applications
• Provides information about fabrication protocols for various biosensor based diagnostic approaches that could be directly implemented to develop a novel biosensor
• Includes the past, present and future status of biosensors, along with information about biosensors currently under clinical trials

Raju Khan is a Senior Principal Scientist and Professor, at CSIR-Advanced Materials and Processes Research Institute, Bhopal. He did his PhD in Chemistry in 2005 from Jamia Millia Islamia, Central University, New Delhi, and Postdoctoral researcher at the “Sensor Research Laboratory” University of the Western Cape, Cape Town. His current research involved synthesizing novel materials to fabricate electrochemical and fluorescence-based biosensors integrated with microfluidics to detect target disease risk biomarkers for health care monitoring. He has published over 150 papers in SCI journal, which attracted over 5500 citations as per Google Scholar, published 45 book chapters in the reputed book Elsevier and Taylor Francis, editing of 28 books from Elsevier and Taylor Francis, and his research has been highlighted in Nature India. He has supervised 5 PhD and 30 undergraduate/postgraduate theses and has supervised 4 numbers of postdoctoral fellows under the scheme of N-PDF, CSIR-Nehru Fellowship, and DST-Women Scientist Projects.

Arpana Parihar is a DST Scientist B at CSIR-Advanced Materials and Processes Research Institute (AMPRI), Bhopal, India. She has 8 years of research and teaching experience and her current research interests include fabrication (Micro/Nano-fabrication) of Bio-devices/bio-medical POCT Devices for early diagnosis of cancer and infectious disease. She has gained significant expertise in the field of 3D cell culture, drug designing, tissue engineering, photodynamic therapy, molecular dynamic simulations, and immunoinformatics.

Dr. Ajeet Kaushik is an Associate Professor of Chemistry at the Department of Chemistry, at Florida Polytechnic University, Florida, United States, as well as an ICS Fellow and Fulbright Specialist. Currently he is exploring nano-enabled technologies for health and environmental monitoring. He has authored or co-authored over 350 publications, published 14 edited books, and has 4 patents, as well as various other editorial roles and international collaborations. Dr. Kaushik’s research interests include green chemistry, catalysis, drug delivery systems, electrochemistry, sensors, and point-of-care sensing for sustainable health and the environment.

Dr. Ashok Kumar is currently working as an Associate Professor in the Department of Biochemistry of All India Institute of Medical Sciences Bhopal. His current research interest is understanding the role of non-coding RNAs and sphingosine-1-phosphate signaling in Head and Neck Cancer. He received his PhD degree from Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS) Lucknow, India. Then, he received postdoctoral training from UCSFBenioff’s Children’s Hospital Oakland & Research Centre, Oakland, CA, USA. Dr. Ashok Kumar’s major area of research work are Cell & Molecular Biology, Cancer Biology, Immunology & Sphingolipid signaling. He has more than 15 years of research experience. He has published more than 50 research articles and 10 book chapters and he has edited two books. He is a member of several international professional societies including American Association of Cancer Research and Fellow of Royal Society of Biology