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9789811378430: Zebrafish: A Model for Marine Peptide Based Drug Screening

Sinopsis

This book offers a comprehensive overview of toxicology, highlighting the significance of peptide-based toxins from marine environments. It discusses the principles of protein-carbohydrate and domain-domain interactions to increase our understanding of toxicology in zebrafish models, as well as drug interaction mechanisms and target definition in drug discovery. It also reviews the structure of marine peptides/toxins and the toxicology of peptide secreting cells and cells that respond to these enzymes, and describes the normal and abnormal toxicology of marine peptides in zebrafish models. Offering insights into the field of proteomics, particularly current practice and research models for solving its many riddles, the book also explains the analytical principles of marine protein-protein and protein-carbohydrate interaction in the context of teratogenicity in target identification in peptide- based drug discovery. Lastly, the book methodically examines the preclinical research on marine proteins/peptides.

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Acerca del autor

Dr. Saravanan Ramachandran is an Assistant Professor of Marine Pharmacology at the Faculty of Allied Health Sciences, Chettinad University Chennai, India. He completed his PhD in Marine Biotechnology at Annamalai University, India. His research interests focus on drugs from marine organisms. He has received two research awards from the Indian Council of Medical Research and the Centre for Marine Living Resources and Ecology, Kochi, India, and he has published 40 research articles in international/national journals. He is a member of Society for Biotechnologists (India), International Neurotoxin Association, holds 2 patents and 1 copyright and has submitted 15 gene sequences to the NCBI. Currently, he is serving as the principal investigator of a research project funded by the Govterment of India Department of Biotechnology. 

Dr. Senthilkumar Rajagopal is an Assistant Professor at the Department of Biochemistry, School of Life Sciences at Rayalaseema University, Kurnool, India. He completed his PhD in Biochemistry at Annamalai University, India, and his postdoctoral fellowship at various Universities in the USA, including the University of Virginia, Harvard and Virginia Commonwealth University. Dr. Rajagopal is a recipient of the Rameshwardasji Birla Smarak Kosh Endowment award from Mumbai Medical Trust, and the Ramalingaswami Re-entry Fellowship from the Department of Biotechnology, Ministry of Science and Technology, Government of India. His research has addressed protein kinase C modulation of calcium channels currents, and was the principal investigator of a major project entitled “G-protein coupled receptor mediated intracellular mechanisms by alcohol-induced digestive disorders in the gastrointestinal tract”. Other interests include G-protein coupled receptor signaling pathways in smooth muscle physiology and neurotransmitters transporters to central nervous system. Dr. Rajagopal is a life member of a numberof respected scientific associations, such as the Indian Society for Atherosclerosis Research (ISAR), The Indian Science Congress Association (ISCA), Society for Free Radical Research India (SFRR), The Indian Society of Cell Biology (ISCB), the American Association of Pharmaceutical Scientists (AAPS) and the Science Advisory Board (SAB), USA.

De la contraportada

This book offers a comprehensive overview of toxicology, highlighting the significance of peptide-based toxins from marine environments. It discusses the principles of protein-carbohydrate and domain-domain interactions to increase our understanding of toxicology in zebrafish models, as well as drug interaction mechanisms and target definition in drug discovery. It also reviews the structure of marine peptides/toxins and the toxicology of peptide secreting cells and cells that respond to these enzymes, and describes the normal and abnormal toxicology of marine peptides in zebrafish models. Offering insights into the field of proteomics, particularly current practice and research models for solving its many riddles, the book also explains the analytical principles of marine protein-protein and protein-carbohydrate interaction in the context of teratogenicity in target identification in peptide- based drug discovery. Lastly, the book methodically examines the preclinical research on marine proteins/peptides.

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9789811378461: Zebrafish: A Model for Marine Peptide Based Drug Screening

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ISBN 10:  9811378460 ISBN 13:  9789811378461
Editorial: Springer-Verlag GmbH, 2020
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Ramachandran, Saravanan; Rajagopal, Senthilkumar
Publicado por Singapore, Springer, ,, 2019
ISBN 10: 9811378436 ISBN 13: 9789811378430
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XI, 73 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Sprache: Englisch. Nº de ref. del artículo: 7118FB

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Saravanan Ramachandran|Senthilkumar Rajagopal
Publicado por Springer Singapore, 2019
ISBN 10: 9811378436 ISBN 13: 9789811378430
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Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Presents the cutting-edge use of zebrafish as a model organism for screening the efficacy of various marine peptides/toxinsDiscusses the potential of various marine peptides/toxins as anti-cancer and cardioprotective agents. Nº de ref. del artículo: 280959938

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ISBN 10: 9811378436 ISBN 13: 9789811378430
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Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book offers a comprehensive overview of toxicology, highlighting the significance of peptide-based toxins from marine environments. It discusses the principles of protein-carbohydrate and domain-domain interactions to increase our understanding of toxicology in zebrafish models, as well as drug interaction mechanisms and target definition in drug discovery. It also reviews the structure of marine peptides/toxins and the toxicology of peptide secreting cells and cells that respond to these enzymes, and describes the normal and abnormal toxicology of marine peptides in zebrafish models. Offering insights into the field of proteomics, particularly current practice and research models for solving its many riddles, the book also explains the analytical principles of marine protein-protein and protein-carbohydrate interaction in the context of teratogenicity in target identification in peptide- based drug discovery. Lastly, the book methodically examines the preclinical research on marine proteins/peptides. 88 pp. Englisch. Nº de ref. del artículo: 9789811378430

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Buch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book offers a comprehensive overview of toxicology, highlighting the significance of peptide-based toxins from marine environments. It discusses the principles of protein-carbohydrate and domain-domain interactions to increase our understanding of toxicology in zebrafish models, as well as drug interaction mechanisms and target definition in drug discovery. It also reviews the structure of marine peptides/toxins and the toxicology of peptide secreting cells and cells that respond to these enzymes, and describes the normal and abnormal toxicology of marine peptides in zebrafish models. Offering insights into the field of proteomics, particularly current practice and research models for solving its many riddles, the book also explains the analytical principles of marine protein-protein and protein-carbohydrate interaction in the context of teratogenicity in target identification in peptide- based drug discovery. Lastly, the book methodically examines the preclinical research on marine proteins/peptides. Nº de ref. del artículo: 9789811378430

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Ramachandran, Saravanan; Rajagopal, Senthilkumar
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ISBN 10: 9811378436 ISBN 13: 9789811378430
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ISBN 10: 9811378436 ISBN 13: 9789811378430
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Buch. Condición: Neu. Neuware -This book offers a comprehensive overview of toxicology, highlighting the significance of peptide-based toxins from marine environments. It discusses the principles of protein-carbohydrate and domain-domain interactions to increase our understanding of toxicology in zebrafish models, as well as drug interaction mechanisms and target definition in drug discovery. It also reviews the structure of marine peptides/toxins and the toxicology of peptide secreting cells and cells that respond to these enzymes, and describes the normal and abnormal toxicology of marine peptides in zebrafish models. Offering insights into the field of proteomics, particularly current practice and research models for solving its many riddles, the book also explains the analytical principles of marine protein-protein and protein-carbohydrate interaction in the context of teratogenicity in target identification in peptide- based drug discovery. Lastly, the book methodically examines the preclinical research on marine proteins/peptides.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 88 pp. Englisch. Nº de ref. del artículo: 9789811378430

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