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Muscle Atrophy: 1088 (Advances in Experimental Medicine and Biology, 1088) - Tapa dura

Libro 395 de 544: Advances in Experimental Medicine and Biology
 
9789811314346: Muscle Atrophy: 1088 (Advances in Experimental Medicine and Biology, 1088)
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ISBN 10: 9811314349 ISBN 13: 9789811314346
Editorial: Springer-Verlag GmbH, 2018

Sinopsis

The book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases morbidity and mortality worldwide. The book is divided into five parts, the first of which describes the general aspects of muscle atrophy including its characteristics, related economic and health burdens, and the current clinical therapy. Secondly, basic aspects of muscle atrophy including the composition, structure and function of skeletal muscle, muscle changes in response to atrophy, and experimental models are summarized. Thirdly, the book reviews the molecular mechanisms of muscle atrophy, including protein degradation and synthesis pathways, noncoding RNAs, inflammatory signaling, oxidative stress, mitochondria signaling, etc. Fourthly, it highlights the pathophysiological mechanisms of muscle atrophy in aging and disease. The book’s fifth and final part covers the diagnosis, treatment strategies, promising agents and future prospects of muscle atrophy. The book will appeal to a broad readership including scientists, undergraduate and graduate students in medicine and cell biology.


"Sinopsis" puede pertenecer a otra edición de este libro.

Acerca del autor

Dr. Junjie Xiao is Principal Investigator and Professor at Regeneration and Ageing Lab in Shanghai University, Shanghai, China.

De la contraportada

The book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases morbidity and mortality worldwide. The book is divided into five parts, the first of which describes the general aspects of muscle atrophy including its characteristics, related economic and health burdens, and the current clinical therapy. Secondly, basic aspects of muscle atrophy including the composition, structure and function of skeletal muscle, muscle changes in response to atrophy, and experimental models are summarized. Thirdly, the book reviews the molecular mechanisms of muscle atrophy, including protein degradation and synthesis pathways, noncoding RNAs, inflammatory signaling, oxidative stress, mitochondria signaling, etc. Fourthly, it highlights the pathophysiological mechanisms of muscle atrophy in aging and disease. The book s fifth and final part covers the diagnosis, treatment strategies, promising agents and future prospects of muscle atrophy. The book will appeal to a broad readership including scientists, undergraduate and graduate students in medicine and cell biology.


"Sobre este título" puede pertenecer a otra edición de este libro.

Editorial
Springer-Verlag GmbH
Año de publicación
2018
Idioma
Inglés
ISBN 10 
9811314349
ISBN 13 
9789811314346
Encuadernación
Tapa dura
Número de edición
1
Número de páginas
639
Editor
Xiao Junjie
Contacto del fabricante
Springer Nature Customer Service Center GmbH
ProductSafety@springernature.com

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