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Endotoxins: Structure, Function and Recognition: 53 (Subcellular Biochemistry, 53) - Tapa dura

Libro 11 de 54: Subcellular Biochemistry
 
9789048190775: Endotoxins: Structure, Function and Recognition: 53 (Subcellular Biochemistry, 53)
Tapa dura
ISBN 10: 9048190770 ISBN 13: 9789048190775
Editorial: Springer, 2010

Sinopsis

Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria. Endotoxins can cause a whole-body inflammatory state, sepsis, leading to low blood pressure, multiple organ dysfunction syndrome and death. This book brings together contributions from researchers in the forefront of these subjects. It is divided into two sections. The first deals with how endotoxins are synthesized and end up on the bacterial surface. The second discussed how endotoxins activate TLR4 and, in turn, how TLR4 generates the molecular signals leading to infectious and inflammatory diseases. The way endotoxins interact with the host cells is fundamental to understanding the mechanism of sepsis, and recent research on these aspects of endotoxins has served to illuminate previously undescribed functions of the innate immune system. This volume presents a description of endotoxins according to their genetic constitution, structure, function and mode of interaction with host cells.

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De la contraportada

Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria. Endotoxins can cause a whole-body inflammatory state, sepsis, leading to low blood pressure, multiple organ dysfunction syndrome and death.This book brings together contributions from researchers in the forefront of these subjects. It is divided into two sections. The first deals with how endotoxins are synthesized and end up on the bacterial surface. The second discussed how endotoxins activate TLR4 and, in turn, how TLR4 generates the molecular signals leading to infectious and inflammatory diseases.The way endotoxins interact with the host cells is fundamental to understanding the mechanism of sepsis, and recent research on these aspects of endotoxins has served to illuminate previously undescribed functions of the innate immune system. This volume presents a description of endotoxins according to their genetic constitution, structure, function and mode of interaction with host cells.

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Editorial
Springer
Año de publicación
2010
Idioma
Inglés
ISBN 10 
9048190770
ISBN 13 
9789048190775
Encuadernación
Tapa dura
Número de páginas
436
Editor
Quinn Peter J., Wang Xiaoyuan
Contacto del fabricante
Springer Nature Customer Service Center GmbH
ProductSafety@springernature.com

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