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Method development using Back-Scattering Interferometry: Analysis of binding between the adenosine A2A receptor and three selective antagonists - Tapa blanda
Sinopsis
Back-scattering interferometry is one of the latest technologies for the study and characterization of interactions between small molecules and more complex drug targets in a native-like environment without any labels or tethers. The information obtained with this technique is of great value since the conditions for the measurement are closest to the real conditions in the body. Principle of signal generation are conformational changes that occur during a binding event between a drug target and its ligand. In this project, the binding interaction between the adenosine A2A receptor and the three antagonists ZM 241385, SCH 58251 and XAC, as well as the agonist (CGS 21680) as positive control was examined. The knowledge about the interactions of the A2AR and its antagonists is of high interest for research of neurological disorders like Parkinson’s disease.
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Back-scattering interferometry is one of the latest technologies for the study and characterization of interactions between small molecules and more complex drug targets in a native-like environment without any labels or tethers. The information obtained with this technique is of great value since the conditions for the measurement are closest to the real conditions in the body. Principle of signal generation are conformational changes that occur during a binding event between a drug target and its ligand. In this project, the binding interaction between the adenosine A2A receptor and the three antagonists ZM 241385, SCH 58251 and XAC, as well as the agonist (CGS 21680) as positive control was examined. The knowledge about the interactions of the A2AR and its antagonists is of high interest for research of neurological disorders like Parkinson’s disease.
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Method development using Back-Scattering Interferometry
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AV Akademikerverlag Aug 2017, 2017
ISBN 10: 6202200804
ISBN 13: 9786202200806
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Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Back-scattering interferometry is one of the latest technologies for the study and characterization of interactions between small molecules and more complex drug targets in a native-like environment without any labels or tethers. The information obtained with this technique is of great value since the conditions for the measurement are closest to the real conditions in the body. Principle of signal generation are conformational changes that occur during a binding event between a drug target and its ligand. In this project, the binding interaction between the adenosine A2A receptor and the three antagonists ZM 241385, SCH 58251 and XAC, as well as the agonist (CGS 21680) as positive control was examined. The knowledge about the interactions of the A2AR and its antagonists is of high interest for research of neurological disorders like Parkinson's disease. 140 pp. Englisch. Nº de ref. del artículo: 9786202200806
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Method development using Back-Scattering Interferometry : Analysis of binding between the adenosine A2A receptor and three selective antagonists
Publicado por
AV Akademikerverlag, 2017
ISBN 10: 6202200804
ISBN 13: 9786202200806
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Librería: AHA-BUCH GmbH, Einbeck, Alemania
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Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Back-scattering interferometry is one of the latest technologies for the study and characterization of interactions between small molecules and more complex drug targets in a native-like environment without any labels or tethers. The information obtained with this technique is of great value since the conditions for the measurement are closest to the real conditions in the body. Principle of signal generation are conformational changes that occur during a binding event between a drug target and its ligand. In this project, the binding interaction between the adenosine A2A receptor and the three antagonists ZM 241385, SCH 58251 and XAC, as well as the agonist (CGS 21680) as positive control was examined. The knowledge about the interactions of the A2AR and its antagonists is of high interest for research of neurological disorders like Parkinson's disease. Nº de ref. del artículo: 9786202200806
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Method development using Back-Scattering Interferometry
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AV Akademikerverlag, 2017
ISBN 10: 6202200804
ISBN 13: 9786202200806
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Librería: Books Puddle, Woodside, NY, Estados Unidos de America
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Condición: New. pp. 140. Nº de ref. del artículo: 26376041291
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Method development using Back-Scattering Interferometry
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AV Akademikerverlag, 2017
ISBN 10: 6202200804
ISBN 13: 9786202200806
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Librería: moluna, Greven, Alemania
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Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Schaffrath BiancaBianca Schaffrath, MSc:Bio and Pharmaceutical Analysis, Master of Science at Hochschule Fresenius Idstein,Applied Chemistry, Bachelor of Science at Hochschule Fresenius Idstein,practical vocational semester at Nottin. Nº de ref. del artículo: 166369763
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Method development using Back-Scattering Interferometry
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AV Akademikerverlag, 2017
ISBN 10: 6202200804
ISBN 13: 9786202200806
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Condición: New. Print on Demand pp. 140. Nº de ref. del artículo: 371085460
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Method development using Back-Scattering Interferometry
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AV Akademikerverlag, 2017
ISBN 10: 6202200804
ISBN 13: 9786202200806
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Librería: Biblios, Frankfurt am main, HESSE, Alemania
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Condición: New. PRINT ON DEMAND pp. 140. Nº de ref. del artículo: 18376041281
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Method development using Back-Scattering Interferometry: Analysis of binding between the adenosine A2A receptor and three selective antagonists
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Paperback. Condición: Brand New. 140 pages. 8.66x5.91x0.32 inches. In Stock. Nº de ref. del artículo: zk6202200804
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Method development using Back-Scattering Interferometry
Publicado por
AV Akademikerverlag Aug 2017, 2017
ISBN 10: 6202200804
ISBN 13: 9786202200806
Nuevo
Taschenbuch
Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Back-scattering interferometry is one of the latest technologies for the study and characterization of interactions between small molecules and more complex drug targets in a native-like environment without any labels or tethers. The information obtained with this technique is of great value since the conditions for the measurement are closest to the real conditions in the body. Principle of signal generation are conformational changes that occur during a binding event between a drug target and its ligand. In this project, the binding interaction between the adenosine A2A receptor and the three antagonists ZM 241385, SCH 58251 and XAC, as well as the agonist (CGS 21680) as positive control was examined. The knowledge about the interactions of the A2AR and its antagonists is of high interest for research of neurological disorders like Parkinson's disease.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 140 pp. Englisch. Nº de ref. del artículo: 9786202200806
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Method development using Back-Scattering Interferometry | Analysis of binding between the adenosine A2A receptor and three selective antagonists
Publicado por
AV Akademikerverlag, 2017
ISBN 10: 6202200804
ISBN 13: 9786202200806
Nuevo
Taschenbuch
Librería: preigu, Osnabrück, Alemania
Calificación del vendedor: 5 de 5 estrellas
Taschenbuch. Condición: Neu. Method development using Back-Scattering Interferometry | Analysis of binding between the adenosine A2A receptor and three selective antagonists | Bianca Schaffrath | Taschenbuch | 140 S. | Englisch | 2017 | AV Akademikerverlag | EAN 9786202200806 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Nº de ref. del artículo: 109668428
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