A variety of human disorders are characterized by, or associated with, tissue hypoxia and manipulation of the HIF pathway has been predicted to significantly alter their clinical course. Early hopes of developing revolutionary PHD-based therapies have yet to translate into novel licensed pharmaceutical agents. Diabetic nephropathy, a progressive development of renal insufficiency in the setting of hyperglycaemia is the major single cause of chronic renal failure (CRF) in which hypoxia plays a critical role. The study investigated the efficacy of cobalt chloride (CoCl2), a Prolyl 4-hydroxylase (PHD) inhibitor in amelioration of renal injury, endothelial dysfunction as well as its effect on hyperglycemia in uninephrectomized diabetic rat. The study signifies the effect of CoCl2 in amelioration of renal failure and associated vascular dysfunctuion.
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A variety of human disorders are characterized by, or associated with, tissue hypoxia and manipulation of the HIF pathway has been predicted to significantly alter their clinical course. Early hopes of developing revolutionary PHD-based therapies have yet to translate into novel licensed pharmaceutical agents. Diabetic nephropathy, a progressive development of renal insufficiency in the setting of hyperglycaemia is the major single cause of chronic renal failure (CRF) in which hypoxia plays a critical role. The study investigated the efficacy of cobalt chloride (CoCl2), a Prolyl 4-hydroxylase (PHD) inhibitor in amelioration of renal injury, endothelial dysfunction as well as its effect on hyperglycemia in uninephrectomized diabetic rat. The study signifies the effect of CoCl2 in amelioration of renal failure and associated vascular dysfunctuion.
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Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A variety of human disorders are characterized by, or associated with, tissue hypoxia and manipulation of the HIF pathway has been predicted to significantly alter their clinical course. Early hopes of developing revolutionary PHD-based therapies have yet to translate into novel licensed pharmaceutical agents. Diabetic nephropathy, a progressive development of renal insufficiency in the setting of hyperglycaemia is the major single cause of chronic renal failure (CRF) in which hypoxia plays a critical role. The study investigated the efficacy of cobalt chloride (CoCl2), a Prolyl 4-hydroxylase (PHD) inhibitor in amelioration of renal injury, endothelial dysfunction as well as its effect on hyperglycemia in uninephrectomized diabetic rat. The study signifies the effect of CoCl2 in amelioration of renal failure and associated vascular dysfunctuion. 252 pp. Englisch. Nº de ref. del artículo: 9786139927982
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Librería: moluna, Greven, Alemania
Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Deshmukh AaishwaryaDr. Aaishwarya B. Deshmukh is having experience of 11+ years in pharmaceutical R&D and Academics. She has also served as executive scientist at Torrent research centre, Project coordinator at Dishman Pharmaceutical. Nº de ref. del artículo: 285683311
Cantidad disponible: Más de 20 disponibles
Librería: AHA-BUCH GmbH, Einbeck, Alemania
Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - A variety of human disorders are characterized by, or associated with, tissue hypoxia and manipulation of the HIF pathway has been predicted to significantly alter their clinical course. Early hopes of developing revolutionary PHD-based therapies have yet to translate into novel licensed pharmaceutical agents. Diabetic nephropathy, a progressive development of renal insufficiency in the setting of hyperglycaemia is the major single cause of chronic renal failure (CRF) in which hypoxia plays a critical role. The study investigated the efficacy of cobalt chloride (CoCl2), a Prolyl 4-hydroxylase (PHD) inhibitor in amelioration of renal injury, endothelial dysfunction as well as its effect on hyperglycemia in uninephrectomized diabetic rat. The study signifies the effect of CoCl2 in amelioration of renal failure and associated vascular dysfunctuion. Nº de ref. del artículo: 9786139927982
Cantidad disponible: 1 disponibles
Librería: preigu, Osnabrück, Alemania
Taschenbuch. Condición: Neu. Effect of CoCl2 in vascular dysfunction of diabetic nephropathy | Aaishwarya Deshmukh (u. a.) | Taschenbuch | 252 S. | Englisch | 2019 | LAP LAMBERT Academic Publishing | EAN 9786139927982 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Nº de ref. del artículo: 116440630
Cantidad disponible: 5 disponibles
Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania
Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -A variety of human disorders are characterized by, or associated with, tissue hypoxia and manipulation of the HIF pathway has been predicted to significantly alter their clinical course. Early hopes of developing revolutionary PHD-based therapies have yet to translate into novel licensed pharmaceutical agents. Diabetic nephropathy, a progressive development of renal insufficiency in the setting of hyperglycaemia is the major single cause of chronic renal failure (CRF) in which hypoxia plays a critical role. The study investigated the efficacy of cobalt chloride (CoCl2), a Prolyl 4-hydroxylase (PHD) inhibitor in amelioration of renal injury, endothelial dysfunction as well as its effect on hyperglycemia in uninephrectomized diabetic rat. The study signifies the effect of CoCl2 in amelioration of renal failure and associated vascular dysfunctuion.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 252 pp. Englisch. Nº de ref. del artículo: 9786139927982
Cantidad disponible: 1 disponibles
Librería: Revaluation Books, Exeter, Reino Unido
Paperback. Condición: Brand New. 252 pages. 8.66x5.91x0.57 inches. In Stock. Nº de ref. del artículo: zk6139927986
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