DNA Encoded Chemical Library: Chemical synthesis, Screening, Drug discovery, High-throughput screening, Combinatorial chemistry, DNA sequencing, Phage display - Tapa blanda

DNA Encoded Chemical Library

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Please note that the content of this book primarily consists of articlesavailable from Wikipedia or other free sources online. DNA EncodedChemical Libraries are a new technology for the synthesis and screeningof collections of chemical compounds of unprecedented size and quality.DEL represents an advance in medicinal chemistry which bridges thefields of combinatorial chemistry and molecular biology. The drivingforce for the development of DEL technology is to improve and streamlinethe drug discovery process in particular early phase discoveryactivities such as target validation and hit discovery. DEL technologyinvolves the conjugation of chemical compounds or building blocks toshort DNA fragments that serve as identification bar codes and in somecases also direct and control the chemical synthesis. The technique, inprinciple, enables the mass creation and interrogation of libraries viaaffinity selection, typically on an immobilized protein target.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 68 pp. Englisch. Nº de ref. del artículo: 9786133930582

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