Addiction Module: Cell Biology, Toxin-antitoxin System - Tapa blanda

Addiction Module

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Please note that the content of this book primarily consists of articlesavailable from Wikipedia or other free sources online. Addiction modulesare toxin-antitoxin systems. Each consists of a pair of genes thatspecify two components: a stable toxin and an unstable antitoxin thatinterferes with the lethal action of the toxin. Found first in E. colion low copy number plasmids, addiction modules are responsible for aprocess called the postsegregational killing effect. When bacteria losethese plasmid(s) (or other extrachromosomal elements), the cured cellsare selectively killed because the unstable antitoxin is degraded fasterthan the more stable toxin. The term 'addiction' is used because thecell depends on the de novo synthesis of the antitoxin for cellsurvival. Thus, addiction modules are implicated in maintaining thestability of extrachromosomal elements.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 76 pp. Englisch. Nº de ref. del artículo: 9786133041219

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