Muscarine: Secondary metabolite, ''Inocybe'', ''Clitocybe'', ''Clitocybe dealbata'', Parasympathomimetic drug, Peripheral nervous system - Tapa blanda

Muscarine

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Please note that the content of this book primarily consists of articlesavailable from Wikipedia or other free sources online. Muscarine ormuscarin is a natural product found in certain mushrooms, particularlyin Inocybe and Clitocybe species, such as the deadly C. dealbata. It wasfirst isolated from Amanita muscaria in 1869. It was the firstparasympathomimetic substance ever studied and causes profoundactivation of the peripheral parasympathetic nervous system that may endin convulsions and death. Being a quaternary amine, Muscarine is lesscompletely absorbed from the gastrointestinal tract than tertiaryamines, but it does cross the blood brain barrier. Muscarine mimics theaction of the neurotransmitter acetylcholine at muscarinic acetylcholinereceptors. Muscarine poisoning is characterized by increased salivationsweating, and tearflow within 15 to 30 minutes after ingestion of themushroom. With large doses, these symptoms may be followed by abdominalpain, severe nausea, diarrhea, blurred vision, and labored breathing.Intoxication generally subsides within 2 hours. Death is rare, but mayresult from cardiac or respiratory failure in severe cases. The specificantidote is atropine.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 68 pp. Englisch. Nº de ref. del artículo: 9786131689420

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