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Sinopsis

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Gene targeting (also, replacement strategy based on homologous recombination) is a genetic technique that uses homologous recombination to change an endogenous gene. The method can be used to delete a gene, remove exons, add a gene, and introduce point mutations. Gene targeting can be permanent or conditional. Conditions can be a specific time during development / life of the organism or limitation to a specific tissue, for example. Gene targeting requires the creation of a specific vector for each gene of interest. However,it can be used for any gene, regardless of transcriptional activity or gene size.

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Présentation de l'éditeur

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Gene targeting (also, replacement strategy based on homologous recombination) is a genetic technique that uses homologous recombination to change an endogenous gene. The method can be used to delete a gene, remove exons, add a gene, and introduce point mutations. Gene targeting can be permanent or conditional. Conditions can be a specific time during development / life of the organism or limitation to a specific tissue, for example. Gene targeting requires the creation of a specific vector for each gene of interest. However,it can be used for any gene, regardless of transcriptional activity or gene size.

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