Artículos relacionados a Model-Based Process Prediction for Predictive-Reactive...
Model-Based Process Prediction for Predictive-Reactive Scheduling in Automated Stem Cell Production - Tapa blanda
Resultados de la búsqueda para Model-Based Process Prediction for Predictive-Reactive...
Imagen del vendedor
Model-Based Process Prediction for Predictive-Reactive Scheduling in Automated Stem Cell Production
Publicado por
Apprimus Verlag Apr 2022, 2022
ISBN 10: 398555059X
ISBN 13: 9783985550593
Nuevo
Taschenbuch
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
Calificación del vendedor: 5 de 5 estrellas
Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Mesenchymal stem cells are highly relevant candidates for cell-based therapies. Since the production is complex and prone to high batch-to-batch variations, processes are increasingly automated. The StemCellDiscovery is a robot-assisted laboratory that allows end-to-end automation of stem cell cultivation processes in small-scale and parallel. Since the investment costs for such systems are high, the return of investment has to be fast to be profitable. Thus, an efficient production is crucial. This thesis investigates whether model-based, predictive-reactive scheduling is suited to increase efficiency in automated production of stem cells. Since the stem cell culture processes can be subject to sudden changes, robotic cultivation systems to date rely mainly on reactive scheduling approaches. While reactive schedulers ensure robust operation, they are not globally optimized and thus often inferior to predictive approaches. This can cause inefficient culture handling, suboptimal harvesting times and unnecessary consumption of system resources. To avoid this, the approach presented here utilizes a mathematical model to extrapolate the growth curves of mesenchymal stem cell cultures based on previous microscopic confluence measurements. This thesis presents a proof-of-concept for a predictive scheduler for generation of optimized schedules based on the model's confluence prediction. The predictive scheduler is complemented by a schedule repair heuristic designed to absorb process disruptions. Both elements are optimized and tested using a detailed simulation model of the production environment. The application of the resulting predictive-reactive scheduling approach is demonstrated by benchmarking against the reactive state of the art. 188 pp. Englisch. Nº de ref. del artículo: 9783985550593
Comprar nuevo
EUR 39,00
Envío por EUR 23,00
Se envía de Alemania a Estados Unidos de America
Se envía de Alemania a Estados Unidos de America
Cantidad disponible: 2 disponibles
Imagen del vendedor
Model-Based Process Prediction for Predictive-Reactive Scheduling in Automated Stem Cell Production
Publicado por
Apprimus Verlag
ISBN 10: 398555059X
ISBN 13: 9783985550593
Nuevo
Kartoniert / Broschiert
Librería: moluna, Greven, Alemania
Calificación del vendedor: 5 de 5 estrellas
Kartoniert / Broschiert. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Mesenchymal stem cells are highly relevant candidates for cell based therapies. Since their production is prone to high batch to batch variations, the processes are often automated. Robotic cultivation systems such as the StemCellDiscovery to date are mainl. Nº de ref. del artículo: 893791274
Comprar nuevo
EUR 39,00
Envío por EUR 48,99
Se envía de Alemania a Estados Unidos de America
Se envía de Alemania a Estados Unidos de America
Cantidad disponible: Más de 20 disponibles
Imagen del vendedor
Model-Based Process Prediction for Predictive-Reactive Scheduling in Automated Stem Cell Production
Publicado por
Apprimus Verlag, Apprimus Verlag Apr 2022, 2022
ISBN 10: 398555059X
ISBN 13: 9783985550593
Nuevo
Taschenbuch
Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania
Calificación del vendedor: 5 de 5 estrellas
Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Mesenchymal stem cells are highly relevant candidates for cell based therapies. Since their production is prone to high batch to batch variations, the processes are often automated. Robotic cultivation systems such as the StemCellDiscovery to date are mainly using reactive production schedulers, which can cause suboptimal resource utilization. This thesis investigates whether model based, predictive reactive scheduling is suited to increase efficiency in automated production of stem cells.Books on Demand GmbH, Überseering 33, 22297 Hamburg 188 pp. Englisch. Nº de ref. del artículo: 9783985550593
Comprar nuevo
EUR 39,00
Envío por EUR 60,00
Se envía de Alemania a Estados Unidos de America
Se envía de Alemania a Estados Unidos de America
Cantidad disponible: 1 disponibles
Imagen del vendedor
Model-Based Process Prediction for Predictive-Reactive Scheduling in Automated Stem Cell Production
Impresión bajo demandaLibrería: AHA-BUCH GmbH, Einbeck, Alemania
Calificación del vendedor: 5 de 5 estrellas
Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Mesenchymal stem cells are highly relevant candidates for cell-based therapies. Since the production is complex and prone to high batch-to-batch variations, processes are increasingly automated. The StemCellDiscovery is a robot-assisted laboratory that allows end-to-end automation of stem cell cultivation processes in small-scale and parallel. Since the investment costs for such systems are high, the return of investment has to be fast to be profitable. Thus, an efficient production is crucial. This thesis investigates whether model-based, predictive-reactive scheduling is suited to increase efficiency in automated production of stem cells. Since the stem cell culture processes can be subject to sudden changes, robotic cultivation systems to date rely mainly on reactive scheduling approaches. While reactive schedulers ensure robust operation, they are not globally optimized and thus often inferior to predictive approaches. This can cause inefficient culture handling, suboptimal harvesting times and unnecessary consumption of system resources. To avoid this, the approach presented here utilizes a mathematical model to extrapolate the growth curves of mesenchymal stem cell cultures based on previous microscopic confluence measurements. This thesis presents a proof-of-concept for a predictive scheduler for generation of optimized schedules based on the model's confluence prediction. The predictive scheduler is complemented by a schedule repair heuristic designed to absorb process disruptions. Both elements are optimized and tested using a detailed simulation model of the production environment. The application of the resulting predictive-reactive scheduling approach is demonstrated by benchmarking against the reactive state of the art. Nº de ref. del artículo: 9783985550593
Comprar nuevo
EUR 39,00
Envío por EUR 61,41
Se envía de Alemania a Estados Unidos de America
Se envía de Alemania a Estados Unidos de America
Cantidad disponible: 1 disponibles
Imagen del vendedor
Model-Based Process Prediction for Predictive-Reactive Scheduling in Automated Stem Cell Production
Librería: preigu, Osnabrück, Alemania
Calificación del vendedor: 5 de 5 estrellas
Taschenbuch. Condición: Neu. Model-Based Process Prediction for Predictive-Reactive Scheduling in Automated Stem Cell Production | Jelena Katherina Ochs | Taschenbuch | Englisch | 2022 | Apprimus Verlag | EAN 9783985550593 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Nº de ref. del artículo: 121573079
Comprar nuevo
EUR 39,00
Envío por EUR 70,00
Se envía de Alemania a Estados Unidos de America
Se envía de Alemania a Estados Unidos de America
Cantidad disponible: 5 disponibles