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PPARγ gene polymorphisms and Infertility: Study of the relation between PPARγ gene polymorphisms and PPARγ protein level in human granoloza cells with ART success - Tapa blanda

Nouri, Mohammad; Sahmani, Mahdi; Dolatkhah, Homayun

 
9783848423521: PPARγ gene polymorphisms and Infertility: Study of the relation between PPARγ gene polymorphisms and PPARγ protein level in human granoloza cells with ART success
Tapa blanda
ISBN 10: 3848423529 ISBN 13: 9783848423521
Editorial: LAP LAMBERT Academic Publishing, 2012

Sinopsis

Infertility is one of the prevalent disorders among communities, especially in women of childbearing age. Today, ART (assisted reproductive technology) such as IVF(in-vitro fertilization) and ICSI(Intra Cytoplasmic Sperm Injection) are used for treatment of infertile couples. Genetic factors have a crucial role in fertility and fetal development and the success of ART can be highly effected by these factors. In the present study, the relationship between HIS447His and Pro12Ala polymorphisms of PPARγ gene and also the PPARγ protein level with the number of oocyte and fertility rate in women candidate for IVF has been investigated. According of the results of this study two common polymorphisms in PPARγ gene may have an important role in-vitro fertilization and possibly rate. In addition no significant relation was found between PPARγ protein concentration in granoloza cell and the ART success rate.

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Reseña del editor

Infertility is one of the prevalent disorders among communities, especially in women of childbearing age. Today, ART (assisted reproductive technology) such as IVF(in-vitro fertilization) and ICSI(Intra Cytoplasmic Sperm Injection) are used for treatment of infertile couples. Genetic factors have a crucial role in fertility and fetal development and the success of ART can be highly effected by these factors. In the present study, the relationship between HIS447His and Pro12Ala polymorphisms of PPARγ gene and also the PPARγ protein level with the number of oocyte and fertility rate in women candidate for IVF has been investigated. According of the results of this study two common polymorphisms in PPARγ gene may have an important role in-vitro fertilization and possibly rate. In addition no significant relation was found between PPARγ protein concentration in granoloza cell and the ART success rate.

Biografía del autor

I am an associate-professor of Clinical Biochemistry in Faculty of Medicine, Tabriz University of Medical Sciences. I have certificate A.R.T. lab. technique, ICSI and IVF from Wife Hospital, Kiel University, Kiel, Germany and also Health Policy, Planning, and Economics from Nuffield Institute, Leeds, UK.

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Editorial
LAP LAMBERT Academic Publishing
Año de publicación
2012
Idioma
Inglés
ISBN 10 
3848423529
ISBN 13 
9783848423521
Encuadernación
Tapa blanda
Número de páginas
92
Contacto del fabricante
no disponible
Persona responsable
no disponible