Ethosomes for Transdermal Delivery: Development of Ethosomal Gel of Curcumin - Tapa blanda

Nanjwade, Basavaraj; K. Patel, Mahesh

 
9783847339748: Ethosomes for Transdermal Delivery: Development of Ethosomal Gel of Curcumin
Tapa blanda
ISBN 10: 3847339745 ISBN 13: 9783847339748
Editorial: LAP LAMBERT Academic Publishing, 2012

Sinopsis

"Ethosomes are soft malleable vesicles composed mainly of phospholipid, ethanol (relatively high concentration) and water. These soft vesicles represents novel vesicular carrier for enhance delivery to / through skin. The size of ethosome vesicles can be modulated from tens of microns to nanometres.” Typically, ethosomes may contain phospholipids with various chemical structures like phosphatidylcholine (PC), hydrogenated PC, phosphatidic acid (PA), phosphatidylserine (PS), phosphatidylethanolamine (PE), phosphatidylglycerol (PPG), phosphatidylinositol (PI), unsaturated PC, alcohol (ethanol or isopropyl alcohol), water and propylene glycol (or other glycols). Such a composition enables delivery of high concentration of active ingredients through skin. Drug delivery can be modulated by altering alcohol: water or alcohol-polyol: water ratio. Some preferred phospholipids are soya phospholipids such as Phospholipon 90 (PL-90). It is usually employed in a range of 0.5-10% w/w. Cholesterol at concentrations ranging between 0.1-1% can also be added to the preparation. Examples of alcohols, which can be used, include ethanol and isopropyl alcohol.

"Sinopsis" puede pertenecer a otra edición de este libro.

Reseña del editor

"Ethosomes are soft malleable vesicles composed mainly of phospholipid, ethanol (relatively high concentration) and water. These soft vesicles represents novel vesicular carrier for enhance delivery to / through skin. The size of ethosome vesicles can be modulated from tens of microns to nanometres." Typically, ethosomes may contain phospholipids with various chemical structures like phosphatidylcholine (PC), hydrogenated PC, phosphatidic acid (PA), phosphatidylserine (PS), phosphatidylethanolamine (PE), phosphatidylglycerol (PPG), phosphatidylinositol (PI), unsaturated PC, alcohol (ethanol or isopropyl alcohol), water and propylene glycol (or other glycols). Such a composition enables delivery of high concentration of active ingredients through skin. Drug delivery can be modulated by altering alcohol: water or alcohol-polyol: water ratio. Some preferred phospholipids are soya phospholipids such as Phospholipon 90 (PL-90). It is usually employed in a range of 0.5-10% w/w. Cholesterol at concentrations ranging between 0.1-1% can also be added to the preparation. Examples of alcohols, which can be used, include ethanol and isopropyl alcohol.

Biografía del autor

Dr. Basavaraj K. Nanjwade has completed his Ph.D from Rajiv Gandhi University of Health Sciences Karnataka, Bangalore. He is the Director of KLE Society’s College of Pharmacy, Nipani, Karnataka, India. He has published 71 papers in reputed national and international journals and 11 Patents. He guided 17 M.Pharm and 7 Ph. D students.

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Editorial
LAP LAMBERT Academic Publishing
Año de publicación
2012
Idioma
Inglés
ISBN 10 
3847339745
ISBN 13 
9783847339748
Encuadernación
Tapa blanda
Número de páginas
164
Contacto del fabricante
no disponible
Persona responsable
no disponible