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Practical Global Optimization Computing Methods in Molecular Modelling: - for Atomic-resolution Structures of Amyloid Fibrils - Tapa blanda
Sinopsis
Due to the unstable, noncrystalline and insoluble nature of some proteins, the technologies such as X-ray crystallography, NMR (nuclear magnetic resonance) spectroscopy and dual polarization interferometry etc sometimes cannot produce the 3D structures of these proteins. In this condition, molecular modeling (MM) might have been the only strategy to get the 3D structures. The non-covalent interactions such as hydrogen bonding (HB), ionic interactions (SB), Van Der Waals forces (VDW), and hydrophobic packing (HP) are driving the proteins to be able to perform their biological functions. The author has found some SBs play a key role in prion diseases revealed from rabbit prion protein. Neurodegenerative diseases are amyloid fibril diseases. This book studies the HB, VDW, HP interactions for MM of amyloid fibrils in global optimization (GO). The GO MM-algorithms of this book should be very useful in materials science, drug design, IT, operations research, biostatistics and bioinformatics etc research fields. This book was written without advanced mathematical formulas thus it is easily readable for people in wide areas of sciences, engineering, IT, medicine, physiology, education,etc
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Due to the unstable, noncrystalline and insoluble nature of some proteins, the technologies such as X-ray crystallography, NMR (nuclear magnetic resonance) spectroscopy and dual polarization interferometry etc sometimes cannot produce the 3D structures of these proteins. In this condition, molecular modeling (MM) might have been the only strategy to get the 3D structures. The non-covalent interactions such as hydrogen bonding (HB), ionic interactions (SB), Van Der Waals forces (VDW), and hydrophobic packing (HP) are driving the proteins to be able to perform their biological functions. The author has found some SBs play a key role in prion diseases revealed from rabbit prion protein. Neurodegenerative diseases are amyloid fibril diseases. This book studies the HB, VDW, HP interactions for MM of amyloid fibrils in global optimization (GO). The GO MM-algorithms of this book should be very useful in materials science, drug design, IT, operations research, biostatistics and bioinformatics etc research fields. This book was written without advanced mathematical formulas thus it is easily readable for people in wide areas of sciences, engineering, IT, medicine, physiology, education,etc
Biografía del autor
Dr Jiapu Zhang (born in 1971) got a Bachelor (1993), two Masters in research (1996, 2000) and a PhD (2005) degrees. During 1996-1998 he lectured in Shandong University, China. Since Feb 2005, he has worked as a Postdocs - Research Scientist - Senior Research Scientist researcher & lecturer/tutor at Melbourne, Ballarat, LaTrobe Universities & CSIRO.
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- EditorialLAP LAMBERT Academic Publishing
- Año de publicación2011
- ISBN 10 3846521396
- ISBN 13 9783846521397
- EncuadernaciónTapa blanda
- IdiomaInglés
- Número de páginas196
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Practical Global Optimization Computing Methods in Molecular Modelling
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LAP LAMBERT Academic Publishing, 2011
ISBN 10: 3846521396
ISBN 13: 9783846521397
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Tapa blanda
Librería: moluna, Greven, Alemania
Calificación del vendedor: 5 de 5 estrellas
Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Zhang JiapuDr Jiapu Zhang (born in 1971) got a Bachelor (1993), two Masters in research (1996, 2000) and a PhD (2005) degrees. During 1996-1998 he lectured in Shandong University, China. Since Feb 2005, he has worked as a Postdocs - . Nº de ref. del artículo: 5496384
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Practical Global Optimization Computing Methods in Molecular Modelling
Publicado por
LAP LAMBERT Academic Publishing Okt 2011, 2011
ISBN 10: 3846521396
ISBN 13: 9783846521397
Nuevo
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Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
Calificación del vendedor: 5 de 5 estrellas
Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Due to the unstable, noncrystalline and insoluble nature of some proteins, the technologies such as X-ray crystallography, NMR (nuclear magnetic resonance) spectroscopy and dual polarization interferometry etc sometimes cannot produce the 3D structures of these proteins. In this condition, molecular modeling (MM) might have been the only strategy to get the 3D structures. The non-covalent interactions such as hydrogen bonding (HB), ionic interactions (SB), Van Der Waals forces (VDW), and hydrophobic packing (HP) are driving the proteins to be able to perform their biological functions. The author has found some SBs play a key role in prion diseases revealed from rabbit prion protein. Neurodegenerative diseases are amyloid fibril diseases. This book studies the HB, VDW, HP interactions for MM of amyloid fibrils in global optimization (GO). The GO MM-algorithms of this book should be very useful in materials science, drug design, IT, operations research, biostatistics and bioinformatics etc research fields. This book was written without advanced mathematical formulas thus it is easily readable for people in wide areas of sciences, engineering, IT, medicine, physiology, education,etc 196 pp. Englisch. Nº de ref. del artículo: 9783846521397
Cantidad disponible: 2 disponibles
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Practical Global Optimization Computing Methods in Molecular Modelling : for Atomic-resolution Structures of Amyloid Fibrils
Publicado por
LAP LAMBERT Academic Publishing, 2011
ISBN 10: 3846521396
ISBN 13: 9783846521397
Nuevo
Taschenbuch
Librería: AHA-BUCH GmbH, Einbeck, Alemania
Calificación del vendedor: 5 de 5 estrellas
Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Due to the unstable, noncrystalline and insoluble nature of some proteins, the technologies such as X-ray crystallography, NMR (nuclear magnetic resonance) spectroscopy and dual polarization interferometry etc sometimes cannot produce the 3D structures of these proteins. In this condition, molecular modeling (MM) might have been the only strategy to get the 3D structures. The non-covalent interactions such as hydrogen bonding (HB), ionic interactions (SB), Van Der Waals forces (VDW), and hydrophobic packing (HP) are driving the proteins to be able to perform their biological functions. The author has found some SBs play a key role in prion diseases revealed from rabbit prion protein. Neurodegenerative diseases are amyloid fibril diseases. This book studies the HB, VDW, HP interactions for MM of amyloid fibrils in global optimization (GO). The GO MM-algorithms of this book should be very useful in materials science, drug design, IT, operations research, biostatistics and bioinformatics etc research fields. This book was written without advanced mathematical formulas thus it is easily readable for people in wide areas of sciences, engineering, IT, medicine, physiology, education,etc. Nº de ref. del artículo: 9783846521397
Cantidad disponible: 1 disponibles
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Practical Global Optimization Computing Methods in Molecular Modelling
Publicado por
LAP LAMBERT Academic Publishing Okt 2011, 2011
ISBN 10: 3846521396
ISBN 13: 9783846521397
Nuevo
Taschenbuch
Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania
Calificación del vendedor: 5 de 5 estrellas
Taschenbuch. Condición: Neu. Neuware -Due to the unstable, noncrystalline and insoluble nature of some proteins, the technologies such as X-ray crystallography, NMR (nuclear magnetic resonance) spectroscopy and dual polarization interferometry etc sometimes cannot produce the 3D structures of these proteins. In this condition, molecular modeling (MM) might have been the only strategy to get the 3D structures. The non-covalent interactions such as hydrogen bonding (HB), ionic interactions (SB), Van Der Waals forces (VDW), and hydrophobic packing (HP) are driving the proteins to be able to perform their biological functions. The author has found some SBs play a key role in prion diseases revealed from rabbit prion protein. Neurodegenerative diseases are amyloid fibril diseases. This book studies the HB, VDW, HP interactions for MM of amyloid fibrils in global optimization (GO). The GO MM-algorithms of this book should be very useful in materials science, drug design, IT, operations research, biostatistics and bioinformatics etc research fields. This book was written without advanced mathematical formulas thus it is easily readable for people in wide areas of sciences, engineering, IT, medicine, physiology, education,etcBooks on Demand GmbH, Überseering 33, 22297 Hamburg 196 pp. Englisch. Nº de ref. del artículo: 9783846521397
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Practical Global Optimization Computing Methods in Molecular Modelling: - for Atomic-resolution Structures of Amyloid Fibrils
Publicado por
LAP LAMBERT Academic Publishing, 2011
ISBN 10: 3846521396
ISBN 13: 9783846521397
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Paperback. Condición: Like New. Like New. book. Nº de ref. del artículo: ERICA79638465213966
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