A New Algorithm for the Management of Dermatofibrosarcoma Protuberans: A Thesis Submitted to the Yale University School of Medicine in Partial ... for the Degree of Doctor of Medicine - Tapa blanda

Goldberg, Carolyn; Narayan, Deepak

 
9783843392365: A New Algorithm for the Management of Dermatofibrosarcoma Protuberans: A Thesis Submitted to the Yale University School of Medicine in Partial ... for the Degree of Doctor of Medicine
Tapa blanda
ISBN 10: 3843392366 ISBN 13: 9783843392365
Editorial: LAP LAMBERT Academic Publishing, 2011

Sinopsis

The purpose of this project was to design an algorithm for the management of Dermatofibrosarcom Protuberans (DFSP.) The National Cancer Center Network guidelines suggest immediate reconstruction in most cases after DFSP resection. We believe this algorithm is inadequate. Due to the infiltrating nature of DFSP, tumor margins are often positive after resection. Immediate reconstruction in the context of residual tumor is problematic because of the risk for spreading microscopic disease and the potential to compromise reconstructive options. Here we examined the prevalence of positive margins on permanent pathology after immediate closure following surgical resection of DFSP. Forty percent of patients who underwent immediate closure were found to have positive margins on permanent pathology. Given these findings, we propose a treatment algorithm focused on more conservative surgical management of DFSP in which negative margins are established before closure. Mohs surgery, which allows for immediate identification of pathology, plays a central role.

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Reseña del editor

The purpose of this project was to design an algorithm for the management of Dermatofibrosarcom Protuberans (DFSP.) The National Cancer Center Network guidelines suggest immediate reconstruction in most cases after DFSP resection. We believe this algorithm is inadequate. Due to the infiltrating nature of DFSP, tumor margins are often positive after resection. Immediate reconstruction in the context of residual tumor is problematic because of the risk for spreading microscopic disease and the potential to compromise reconstructive options. Here we examined the prevalence of positive margins on permanent pathology after immediate closure following surgical resection of DFSP. Forty percent of patients who underwent immediate closure were found to have positive margins on permanent pathology. Given these findings, we propose a treatment algorithm focused on more conservative surgical management of DFSP in which negative margins are established before closure. Mohs surgery, which allows for immediate identification of pathology, plays a central role.

Biografía del autor

Carolyn Goldberg graduated from Brown University in 2005 and from Yale School of Medicine in 2010. She is currently a resident in Plastic and Reconstructive Surgery at the University of Wisconsin.

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Editorial
LAP LAMBERT Academic Publishing
Año de publicación
2011
Idioma
Inglés
ISBN 10 
3843392366
ISBN 13 
9783843392365
Encuadernación
Tapa blanda
Número de páginas
52
Contacto del fabricante
no disponible
Persona responsable
no disponible