Artículos relacionados a Sinus node inhibitors: A new concept in angina pectoris

Sinus node inhibitors: A new concept in angina pectoris - Tapa blanda

W. J. Remme, Å. Hjalmarson

 
9783798508613: Sinus node inhibitors: A new concept in angina pectoris
Tapa blanda
ISBN 10: 3798508615 ISBN 13: 9783798508613
Editorial: Steinkopff, 1991

Sinopsis

Although surgical and catheter-based revascularization techniques have substan tially improved today’s therapeutic potential in ischemic heart disease, in the majority of patients treatment will be conservative for a number of reasons, the cost-effectiveness of non-pharmacological approaches being of major importance. During the last two decades, drug development for ischemic heart disease has been impressive and many new compounds have been added to our therapeutic armamentarium. Nevertheless, where mode of action is concerned, it is interesting to note that, despite all these efforts, we are still confined to three categories of drugs. Antithrombotics and platelet-active agents aside, these concern nitrates, betablocking drugs and calcium antagonists, agents which reduce ischemia by diminishing cardiac work or wall stress,. thereby affecting myocardial oxygen demand and/or by improving coronary blood flow. Alone or in combination, these agents have proved to be efficacious in the treatment of angina pectoris or other symptoms of ischemic heart disease in a number of patients, but certainly not in all. Moreover, as side-effects are often a problem with current antianginal compounds, the physician may find himself restricted in his therapeutic capabilities and in need of new and, preferably, alternative forms of pharmacological treatment.

"Sinopsis" puede pertenecer a otra edición de este libro.

Reseña del editor

Although surgical and catheter-based revascularization techniques have substan­ tially improved today's therapeutic potential in ischemic heart disease, in the majority of patients treatment will be conservative for a number of reasons, the cost-effectiveness of non-pharmacological approaches being of major importance. During the last two decades, drug development for ischemic heart disease has been impressive and many new compounds have been added to our therapeutic armamentarium. Nevertheless, where mode of action is concerned, it is interesting to note that, despite all these efforts, we are still confined to three categories of drugs. Antithrombotics and platelet-active agents aside, these concern nitrates, betablocking drugs and calcium antagonists, agents which reduce ischemia by diminishing cardiac work or wall stress,. thereby affecting myocardial oxygen demand and/or by improving coronary blood flow. Alone or in combination, these agents have proved to be efficacious in the treatment of angina pectoris or other symptoms of ischemic heart disease in a number of patients, but certainly not in all. Moreover, as side-effects are often a problem with current antianginal compounds, the physician may find himself restricted in his therapeutic capabilities and in need of new and, preferably, alternative forms of pharmacological treatment.

Reseña del editor

This volume addresses a novel concept in antiischemic therapy, sinus node inhibition. The sinus node inhibitors which have thus far been developed, including the clonidine-derivative alinidine, falipamil and the benzazepinone derivative UL FS 49, are discussed in detail.

"Sobre este título" puede pertenecer a otra edición de este libro.

Editorial
Steinkopff
Año de publicación
1991
Idioma
Inglés
ISBN 10 
3798508615
ISBN 13 
9783798508613
Encuadernación
Tapa blanda
Número de páginas
76
Contacto del fabricante
no disponible
Persona responsable
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