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Sinopsis
Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal is a prerequisite to trigger the growth and differentiation of responding cells in space and time. Bone morphogenetic proteins (BMPs), also called growth and differentiation factors (GDFs), originally identified from bone have been successfully used to regenerate the bone in humans. Most recent preclinical data suggests that BMPs have a potential to provide protection against inflammation and fibrosis in acute and chronic injury of parenchymal tissues when applied systemically to sustain the function of kidney and liver. The application of BMPs from a local to systemic utility is a rapidly growing field, gaining interest among researchers and biotech entrepreneurs.
In this volume, we summarize the advances made on the local and systemic use of BMPs including chapters covering the regulation of BMP-signalling pathways, biological actions of BMPs in bone, cartilage and teeth, as well as clinical applications and potential systemic use of BMPs for tissues beyond bone.
This volume is of interest to researchers from immunology, cell biology, biochemistry, and clinicians from orthopedics and dentistry, as well as to research managers from biotech and pharmaceutical companies.
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De la contraportada
Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal is a prerequisite to trigger the growth and differentiation of responding cells in space and time. Bone morphogenetic proteins (BMPs), also called growth and differentiation factors (GDFs), originally identified from bone have been successfully used to regenerate the bone in humans. Most recent preclinical data suggests that BMPs have a potential to provide protection against inflammation and fibrosis in acute and chronic injury of parenchymal tissues when applied systemically to sustain the function of kidney and liver. The application of BMPs from a local to systemic utility is a rapidly growing field, gaining interest among researchers and biotech entrepreneurs.
In this volume, we summarize the advances made on the local and systemic use of BMPs including chapters covering the regulation of BMP-signalling pathways, biological actions of BMPs in bone, cartilage and teeth, as well as clinical applications and potential systemic use of BMPs for tissues beyond bone.
This volume is of interest to researchers from immunology, cell biology, biochemistry, and clinicians from orthopedics and dentistry, as well as to research managers from biotech and pharmaceutical companies.
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- EditorialSpringer Basel AG
- Año de publicación2008
- ISBN 10 3764385510
- ISBN 13 9783764385514
- EncuadernaciónTapa dura
- IdiomaInglés
- Número de páginas364
- EditorSampath Kuber T., Vukicevic Slobodan
- Contacto del fabricanteno disponible
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BONE MORPHOGENETIC PROTEINS: FROM LOCAL TO SYSTEMIC THERAPEUTICS
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Bone Morphogenetic Proteins: From Local to Systemic Therapeutics
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ISBN 10: 3764385510
ISBN 13: 9783764385514
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Bone Morphogenetic Proteins
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Bone Morphogenetic Proteins
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Bone Morphogenetic Proteins: From Local To Systemic Therapeutics
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Bone Morphogenetic Proteins
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Bone Morphogenetic Proteins: From Local to Systemic Therapeutics
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Bone Morphogenetic Proteins: From Local To Systemic Therapeutics (progress In Inflammation Research) (progress In Inflammation Research)
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Bone Morphogenetic Proteins: From Local to Systemic Therapeutics (Progress in Inflammation Research) (Progress in Inflammation Research)
Publicado por
Birkh�¤user Basel, 2008
ISBN 10: 3764385510
ISBN 13: 9783764385514
Antiguo o usado
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Bone Morphogenetic Proteins: From Local To Systemic Therapeutics (Progress In Inflammation Research) (Progress In Inflammation Research) (Progress In Inflammation Research)
Librería: Romtrade Corp., STERLING HEIGHTS, MI, Estados Unidos de America
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Condición: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide. Nº de ref. del artículo: ABNR-177850
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