The Hereditary Basis of Allergic Diseases (Progress in Inflammation Research) - Tapa dura

 
9783764364021: The Hereditary Basis of Allergic Diseases (Progress in Inflammation Research)
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ISBN 10: 3764364025 ISBN 13: 9783764364021
Editorial: Birkhäuser, 2002

Sinopsis

Allergic diseases are complex and involve a range of environmental factors interacting with a susceptible genotype. The familial clustering of diseases, such as asthma and hay fever, has been recognised for over two centuries, but identification of the genetic basis to this had to await the molecular biological revolution. Estimates of the contribution that genetic factors make to asthma susceptibility range from 35% to 70%. For the majority of allergic diseases, segregation analysis has not identified a consistent Mendelian pattern of inheritance, which, when combined with multiple phenotypes and environmental interactions, has made identifying candidate genes especially difficult and, at times, controversial. Part of the difficulty has been lack of agreement over phenotype definitions, reduced power of studies to predict linkage and association, and, importantly, lack of true heterogeneity between populations. Despite these difficulties, the last decade has witnessed enormous progress in this field.

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Reseña del editor

Allergic diseases are complex and involve a range of environmental factors interacting with a susceptible genotype. The familial clustering of diseases, such as asthma and hay fever, has been recognised for over two centuries, but identification of the genetic basis to this had to await the molecular biological revolution. Estimates of the contribution that genetic factors make to asthma susceptibility range from 35% to 70%. For the majority of allergic diseases, segregation analysis has not identified a consistent Mendelian pattern of inheritance, which, when combined with multiple phenotypes and environmental interactions, has made identifying candidate genes especially difficult and, at times, controversial. Part of the difficulty has been lack of agreement over phenotype definitions, reduced power of studies to predict linkage and association, and, importantly, lack of true heterogeneity between populations. Despite these difficulties, the last decade has witnessed enormous progress in this field.

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Editorial
Birkhäuser
Año de publicación
2002
Idioma
Inglés
ISBN 10 
3764364025
ISBN 13 
9783764364021
Encuadernación
Tapa dura
Número de páginas
200
Editor
Holloway John W., Holgate Stephen T.
Contacto del fabricante
no disponible
Persona responsable
no disponible

Otras ediciones populares con el mismo título

9783034894524: The Hereditary Basis of Allergic Diseases (Progress in Inflammation Research)

Edición Destacada

ISBN 10:  303489452X ISBN 13:  9783034894524
Editorial: Birkhäuser, 2012
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