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Sinopsis
Research in the pharmaceutical industry today is in many respects quite different from what it used to be only fifteen years ago. There have been dramatic changes in approaches for identifying new chemical entities with a desired biological activity. While chemical modification of existing leads was the most important approach in the 1970s and 1980s, high-throughput screening and structure-based design are now major players among a multitude of methods used in drug discov ery. Quite often, companies favor one of these relatively new approaches over the other, e.g., screening over rational design, or vice versa, but we believe that an intelligent and concerted use of several or all methods currently available to drug discovery will be more successful in the medium term. What has changed most significantly in the past few years is the time available for identifying new chemical entities. Because of the high costs of drug discovery projects, pressure for maximum success in the shortest possible time is higher than ever. In addition, the multidisciplinary character of the field is much more pronounced today than it used to be. As a consequence, researchers and project managers in the pharmaceutical industry should have a solid knowledge of the more important methods available to drug discovery, because it is the rapidly and intelligently combined use of these which will determine the success or failure of preclinical projects.
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De la contraportada
This volume offers a broad and interdisciplinary view of modern approaches to drug discovery as used by pharmaceutical companies and research institutes. It comprehensively covers proteomics, bioinformatics, screening techniques such as high-throughput-, natural compounds-, and NMR-based-screenings, combinatorial chemistry, compound library design, ligand- and structure-based drug design and pharmacokinetic approaches. Each of the thirteen chapters reviews the theory, background and application of a key technology in drug discovery, complemented by an extensive list of references to the original literature.
This concise source of information will be useful for researchers, both in industry and academia, as well as students in the fields of medicinal, pharmaceutical and computational chemistry, bioinformatics, biochemistry, molecular biology and pharmacology.
Features and benefits
- Structure-based drug design, molecular modeling, bioinformatics, screening methods, combinatorial chemistry and physicochemical concepts in drug discovery are comprehensively covered.
- The volume is written from the viewpoint of the "drug researcher" working in the pharmaceutical industry, and also presents chapters on novel approaches developed in academia.
- Offers high practical value for young scientists who need a quick introduction to the topic.
- Provides an overview of the drug discovery process, particularly for specialized scientists working in drug discovery and pharma-managers.
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Modern Methods of Drug Discovery (Experientia Supplementum, 93, Band 93)
Librería: Ammareal, Morangis, Francia
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Hardcover. Condición: Très bon. Ancien livre de bibliothèque avec équipements. Edition 2002. Ammareal reverse jusqu'à 15% du prix net de cet article à des organisations caritatives. ENGLISH DESCRIPTION Book Condition: Used, Very good. Former library book. Edition 2002. Ammareal gives back up to 15% of this item's net price to charity organizations. Nº de ref. del artículo: F-979-756
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Modern Methods of Drug Discovery
Publicado por
Birkhäuser Basel, 2002
ISBN 10: 376436081X
ISBN 13: 9783764360818
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Librería: Buchpark, Trebbin, Alemania
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Modern Methods of Drug Discovery
Publicado por
Birkhauser, Germany, 2002
ISBN 10: 376436081X
ISBN 13: 9783764360818
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Librería: The Book Exchange, Macclesfield, CHESH, Reino Unido
Calificación del vendedor: 4 de 5 estrellas
Hardcover. Condición: Near Fine. 376436081X. Ex library, laminated, pictorial board hardcover. 292 pages, index, illustrated with charts, tables and diagrams. A modern approach to drug discovery as used by pharmaceutical companies and research institutes. It comprehensively covers proteomics, bioinformatics, screening techniques such as high-throughput-, natural compounds-, and NMR-based-screenings, combinatorial chemistry, compound library design, ligand- and structure-based drug design and pharmacokinetic approaches. Each chapter reviews the theory, background and application of a key technology in drug discovery, complemented by an extensive list of references to the original literature. For researchers, in industry and academia, students of pharmaceutical and computational chemistry, bioinformatics, biochemistry, molecular biology and pharmacology. Contents as new, clean, tight and bright. Book. Nº de ref. del artículo: 027095
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Modern Methods of Drug Discovery (Experientia Supplementum) (Volume 93)
Librería: Anybook.com, Lincoln, Reino Unido
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Condición: Good. Volume 93. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. Clean from markings. In good all round condition. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,900grams, ISBN:9783764360818. Nº de ref. del artículo: 7068289
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Modern Methods of Drug Discovery
Edición internacionalLibrería: Basi6 International, Irving, TX, Estados Unidos de America
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Condición: Brand New. New.SoftCover International edition. Different ISBN and Cover image but contents are same as US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service. Nº de ref. del artículo: ABEJUNE24-277216
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Modern Methods of Drug Discovery
Impresión bajo demandaLibrería: moluna, Greven, Alemania
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Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Research in the pharmaceutical industry today is in many respects quite different from what it used to be only fifteen years ago. There have been dramatic changes in approaches for identifying new chemical entities with a desired biological activity. While . Nº de ref. del artículo: 5279275
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Modern Methods of Drug Discovery
Librería: Ria Christie Collections, Uxbridge, Reino Unido
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Modern Methods of Drug Discovery
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Springer, Basel, Birkhäuser Basel, Birkhäuser Dez 2002, 2002
ISBN 10: 376436081X
ISBN 13: 9783764360818
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Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
Calificación del vendedor: 5 de 5 estrellas
Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Research in the pharmaceutical industry today is in many respects quite different from what it used to be only fifteen years ago. There have been dramatic changes in approaches for identifying new chemical entities with a desired biological activity. While chemical modification of existing leads was the most important approach in the 1970s and 1980s, high-throughput screening and structure-based design are now major players among a multitude of methods used in drug discov ery. Quite often, companies favor one of these relatively new approaches over the other, e.g., screening over rational design, or vice versa, but we believe that an intelligent and concerted use of several or all methods currently available to drug discovery will be more successful in the medium term. What has changed most significantly in the past few years is the time available for identifying new chemical entities. Because of the high costs of drug discovery projects, pressure for maximum success in the shortest possible time is higher than ever. In addition, the multidisciplinary character of the field is much more pronounced today than it used to be. As a consequence, researchers and project managers in the pharmaceutical industry should have a solid knowledge of the more important methods available to drug discovery, because it is the rapidly and intelligently combined use of these which will determine the success or failure of preclinical projects. 292 pp. Englisch. Nº de ref. del artículo: 9783764360818
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Modern Methods of Drug Discovery
Librería: AHA-BUCH GmbH, Einbeck, Alemania
Calificación del vendedor: 5 de 5 estrellas
Buch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Research in the pharmaceutical industry today is in many respects quite different from what it used to be only fifteen years ago. There have been dramatic changes in approaches for identifying new chemical entities with a desired biological activity. While chemical modification of existing leads was the most important approach in the 1970s and 1980s, high-throughput screening and structure-based design are now major players among a multitude of methods used in drug discov ery. Quite often, companies favor one of these relatively new approaches over the other, e.g., screening over rational design, or vice versa, but we believe that an intelligent and concerted use of several or all methods currently available to drug discovery will be more successful in the medium term. What has changed most significantly in the past few years is the time available for identifying new chemical entities. Because of the high costs of drug discovery projects, pressure for maximum success in the shortest possible time is higher than ever. In addition, the multidisciplinary character of the field is much more pronounced today than it used to be. As a consequence, researchers and project managers in the pharmaceutical industry should have a solid knowledge of the more important methods available to drug discovery, because it is the rapidly and intelligently combined use of these which will determine the success or failure of preclinical projects. Nº de ref. del artículo: 9783764360818
Cantidad disponible: 1 disponibles
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Modern Methods of Drug Discovery
Librería: California Books, Miami, FL, Estados Unidos de America
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Condición: New. Nº de ref. del artículo: I-9783764360818
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