History, importance, and some basic concept of chirality - Tapa blanda

Bhoi, Manoj N.; Borad, Mayuri A.; Patel, Hitesh D.

 
9783659935305: History, importance, and some basic concept of chirality
Tapa blanda
ISBN 10: 3659935301 ISBN 13: 9783659935305
Editorial: LAP LAMBERT Academic Publishing, 2016

Sinopsis

Chiral drugs are currently 50% used and near 90% of the last ones are marketed as racemates consisting of an equimolar mixture of two enantiomers. While they have the same scaffold, but they shows different biological activities such as pharmacology, toxicology, pharmacokinetics, metabolism etc. Therefore, it is significant to endorse the chiral separation and analysis of racemic drugs either in industry or in the clinic so as to eliminate the unwanted isomer from the groundwork and to find an optimal treatment and a right therapeutic control for the patient. In this article, we have briefly discussed the history of chirality, importance, and some basic concept of them. We have also included the importance of separation and various resolution methods.

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Acerca del autor

Manoj N. Bhoi was obtained his M.Sc. degree in organic chemistry in 2012 both from the Gujarat University, Ahmedabad (India). Currently, he is pursuing his Ph.D. under the guidance of Dr. Hitesh D. Patel at the Chemistry Department of the Gujarat University, Ahmedabad. His research focuses on multicomponent reactions and asymmetric synthesis.

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Editorial
LAP LAMBERT Academic Publishing
Año de publicación
2016
Idioma
Inglés
ISBN 10 
3659935301
ISBN 13 
9783659935305
Encuadernación
Tapa blanda
Número de páginas
60
Contacto del fabricante
no disponible
Persona responsable
no disponible