Advanced Biosensor Modelling with DNA Application: Accurate Modeling of DNA Hybridization - Tapa blanda

Karimi Feizabadi, Hediyeh; Rahmani, Rasoul; Ahmadi, Mohammad Taghi

 
9783659590238: Advanced Biosensor Modelling with DNA Application: Accurate Modeling of DNA Hybridization
Tapa blanda
ISBN 10: 3659590231 ISBN 13: 9783659590238
Editorial: LAP LAMBERT Academic Publishing, 2014

Sinopsis

Nowadays,detection of a single-base polymorphism is thought to be the key for diagnosis of about 400 genetic diseases and,realization of personalized medicine in order to develop therapeutics.The other hand,the integration of new emerging nanomaterials(graphene)with sensors and devices have revealed an enormous potential for the future application of highly sensitive and selective DNA biosensors.All these approaches open up the routes for genetic researchers to understand the progression and early screening of diseases,or forensic analysis by tailoring the electrical properties of graphene,which make the controlled design of these sensors essential.In this research study, numerical model of the graphene-based liquid-gated sensors with DNA sensing application is developed to help in understanding the sensing mechanism of these sensors which is the matter of dispute these days.The results are compared with the experimental work and an acceptable agreement is observed. We found that numerical modeling needs optimization to be closer to the realistic results.So, particle swarm optimization technique is used to achieve a more accurate and reliable model for DNA hybridization detection.

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Reseña del editor

Nowadays,detection of a single-base polymorphism is thought to be the key for diagnosis of about 400 genetic diseases and,realization of personalized medicine in order to develop therapeutics.The other hand,the integration of new emerging nanomaterials(graphene)with sensors and devices have revealed an enormous potential for the future application of highly sensitive and selective DNA biosensors.All these approaches open up the routes for genetic researchers to understand the progression and early screening of diseases,or forensic analysis by tailoring the electrical properties of graphene,which make the controlled design of these sensors essential.In this research study, numerical model of the graphene-based liquid-gated sensors with DNA sensing application is developed to help in understanding the sensing mechanism of these sensors which is the matter of dispute these days.The results are compared with the experimental work and an acceptable agreement is observed. We found that numerical modeling needs optimization to be closer to the realistic results.So, particle swarm optimization technique is used to achieve a more accurate and reliable model for DNA hybridization detection.

Biografía del autor

Dr. Hediyeh Karimi received the B.Sc. degree in Electrical Engineering- Electronics from the IAU university, Iran, in 2008 and M.Sc. and Ph.D. degrees in Electrical Engineering from school of Malaysia-Japan International Institute of Technology (MJIIT),Universiti Teknologi Malaysia(UTM),Malaysia,in 2008 and 2011 respectively.

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Editorial
LAP LAMBERT Academic Publishing
Año de publicación
2014
Idioma
Inglés
ISBN 10 
3659590231
ISBN 13 
9783659590238
Encuadernación
Tapa blanda
Número de páginas
88
Contacto del fabricante
no disponible
Persona responsable
no disponible