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Modelling of an Implantable Device for Localized Hyperthermia: A Finite Element Analysis - Tapa blanda
Sinopsis
A mathematical framework on relaxation losses of heating of magnetite nanoparticles synthesized with Polydimethylsiloxane (PDMS) gel encasement is presented. Numerical solution of the mathematical model showed explicit dependence of the temperature rise of the device on frequency and amplitude of the external applied field, relaxation time and volume fraction of the nanoparticles. Hyperthermia therapeutic temperature of 41 – 46oC can be achieved with an external field of frequency and amplitude in the ranges 2.16 – 2.19 kHz and 9.77 – 9.89 kA/m respectively. Also, viscosity and volume fraction of the nanoparticles lies in the ranges 1.1 – 1.2 mPa.s and 0.12 – 0.14 respectively. Simulation of the heat diffusion profile of the implant and its surrounding tumor was done using Abaqus/CAE 6.9, a finite element simulation package. In 2D, the results showed that for maximum generated temperatures of 52oC and 55oC, the tumor temperature was maintained within the therapeutic range for more than thirty minutes in conformity with predicted theory. However, the tumor temperature falls below the therapeutic range for generated temperature of 45oC.
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A mathematical framework on relaxation losses of heating of magnetite nanoparticles synthesized with Polydimethylsiloxane (PDMS) gel encasement is presented. Numerical solution of the mathematical model showed explicit dependence of the temperature rise of the device on frequency and amplitude of the external applied field, relaxation time and volume fraction of the nanoparticles. Hyperthermia therapeutic temperature of 41 - 46oC can be achieved with an external field of frequency and amplitude in the ranges 2.16 - 2.19 kHz and 9.77 - 9.89 kA/m respectively. Also, viscosity and volume fraction of the nanoparticles lies in the ranges 1.1 - 1.2 mPa.s and 0.12 - 0.14 respectively. Simulation of the heat diffusion profile of the implant and its surrounding tumor was done using Abaqus/CAE 6.9, a finite element simulation package. In 2D, the results showed that for maximum generated temperatures of 52oC and 55oC, the tumor temperature was maintained within the therapeutic range for more than thirty minutes in conformity with predicted theory. However, the tumor temperature falls below the therapeutic range for generated temperature of 45oC.
Biografía del autor
Bugase Jonas was born on May 9th, 1985. He graduated with a BSc in Applied Physics from University for Development Studies, Tamale. Jonas attained an MSc in Theoretical Physics at the African University of Science and Technology, Abuja and currently a lecturer at his BSc alma mater. His research interest is in superconductivity and magnetism.
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Modelling of an Implantable Device for Localized Hyperthermia
Publicado por
LAP LAMBERT Academic Publishing Mai 2013, 2013
ISBN 10: 3659366161
ISBN 13: 9783659366161
Nuevo
Taschenbuch
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
Calificación del vendedor: 5 de 5 estrellas
Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A mathematical framework on relaxation losses of heating of magnetite nanoparticles synthesized with Polydimethylsiloxane (PDMS) gel encasement is presented. Numerical solution of the mathematical model showed explicit dependence of the temperature rise of the device on frequency and amplitude of the external applied field, relaxation time and volume fraction of the nanoparticles. Hyperthermia therapeutic temperature of 41 46oC can be achieved with an external field of frequency and amplitude in the ranges 2.16 2.19 kHz and 9.77 9.89 kA/m respectively. Also, viscosity and volume fraction of the nanoparticles lies in the ranges 1.1 1.2 mPa.s and 0.12 0.14 respectively. Simulation of the heat diffusion profile of the implant and its surrounding tumor was done using Abaqus/CAE 6.9, a finite element simulation package. In 2D, the results showed that for maximum generated temperatures of 52oC and 55oC, the tumor temperature was maintained within the therapeutic range for more than thirty minutes in conformity with predicted theory. However, the tumor temperature falls below the therapeutic range for generated temperature of 45oC. 76 pp. Englisch. Nº de ref. del artículo: 9783659366161
Cantidad disponible: 2 disponibles
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Modelling of an Implantable Device for Localized Hyperthermia : A Finite Element Analysis
Publicado por
LAP LAMBERT Academic Publishing, 2013
ISBN 10: 3659366161
ISBN 13: 9783659366161
Nuevo
Taschenbuch
Librería: AHA-BUCH GmbH, Einbeck, Alemania
Calificación del vendedor: 5 de 5 estrellas
Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - A mathematical framework on relaxation losses of heating of magnetite nanoparticles synthesized with Polydimethylsiloxane (PDMS) gel encasement is presented. Numerical solution of the mathematical model showed explicit dependence of the temperature rise of the device on frequency and amplitude of the external applied field, relaxation time and volume fraction of the nanoparticles. Hyperthermia therapeutic temperature of 41 46oC can be achieved with an external field of frequency and amplitude in the ranges 2.16 2.19 kHz and 9.77 9.89 kA/m respectively. Also, viscosity and volume fraction of the nanoparticles lies in the ranges 1.1 1.2 mPa.s and 0.12 0.14 respectively. Simulation of the heat diffusion profile of the implant and its surrounding tumor was done using Abaqus/CAE 6.9, a finite element simulation package. In 2D, the results showed that for maximum generated temperatures of 52oC and 55oC, the tumor temperature was maintained within the therapeutic range for more than thirty minutes in conformity with predicted theory. However, the tumor temperature falls below the therapeutic range for generated temperature of 45oC. Nº de ref. del artículo: 9783659366161
Cantidad disponible: 1 disponibles
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Modelling of an Implantable Device for Localized Hyperthermia
Publicado por
LAP LAMBERT Academic Publishing, 2013
ISBN 10: 3659366161
ISBN 13: 9783659366161
Nuevo
Tapa blanda
Librería: moluna, Greven, Alemania
Calificación del vendedor: 5 de 5 estrellas
Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Bugase JonasBugase Jonas was born on May 9th, 1985. He graduated with a BSc in Applied Physics from University for Development Studies, Tamale. Jonas attained an MSc in Theoretical Physics at the African University of Science and Tec. Nº de ref. del artículo: 5151415
Cantidad disponible: Más de 20 disponibles
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Modelling of an Implantable Device for Localized Hyperthermia
Publicado por
LAP LAMBERT Academic Publishing Mai 2013, 2013
ISBN 10: 3659366161
ISBN 13: 9783659366161
Nuevo
Taschenbuch
Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania
Calificación del vendedor: 5 de 5 estrellas
Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -A mathematical framework on relaxation losses of heating of magnetite nanoparticles synthesized with Polydimethylsiloxane (PDMS) gel encasement is presented. Numerical solution of the mathematical model showed explicit dependence of the temperature rise of the device on frequency and amplitude of the external applied field, relaxation time and volume fraction of the nanoparticles. Hyperthermia therapeutic temperature of 41 ¿ 46oC can be achieved with an external field of frequency and amplitude in the ranges 2.16 ¿ 2.19 kHz and 9.77 ¿ 9.89 kA/m respectively. Also, viscosity and volume fraction of the nanoparticles lies in the ranges 1.1 ¿ 1.2 mPa.s and 0.12 ¿ 0.14 respectively. Simulation of the heat diffusion profile of the implant and its surrounding tumor was done using Abaqus/CAE 6.9, a finite element simulation package. In 2D, the results showed that for maximum generated temperatures of 52oC and 55oC, the tumor temperature was maintained within the therapeutic range for more than thirty minutes in conformity with predicted theory. However, the tumor temperature falls below the therapeutic range for generated temperature of 45oC.Books on Demand GmbH, Überseering 33, 22297 Hamburg 76 pp. Englisch. Nº de ref. del artículo: 9783659366161
Cantidad disponible: 1 disponibles