Formulation and Characterization of Ranitidine Hydrochloride: Mucoadhesive Drug Delivery System - Tapa blanda

Asati, Ashok; Verma, Sofiya; Chaurasia, Sandhya

 
9783659195679: Formulation and Characterization of Ranitidine Hydrochloride: Mucoadhesive Drug Delivery System
Tapa blanda
ISBN 10: 3659195677 ISBN 13: 9783659195679
Editorial: LAP LAMBERT Academic Publishing, 2012

Sinopsis

prepare and evaluate mucoadhesive drug delivery system of Ranitidine hydrochloride tablet using hydrophilic polymers in order to reduce dose frequency to match the initial release of the drug with the conventional dosage form. The formulation was designed adopting optimization technique, which helps in setting up experiments in such a manner that the information is obtained as efficiently and precisely as possible. Initially, considering buoyancy as the main criteria, blank tablets were compressed for different formulae with various polymers HPMC K 15 M, HPMC K 100 M, Carbopol 934. The tablets were prepared by direct compression method and evaluated for Ranitdine content, in vitro release profile and buoyancy. The dissolution study was carried out in simulated gastric fluid using USP dissolution test apparatus employing paddle stirrer.. This indicates the suitability of the technique chosen for the present dosage form.

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Reseña del editor

prepare and evaluate mucoadhesive drug delivery system of Ranitidine hydrochloride tablet using hydrophilic polymers in order to reduce dose frequency to match the initial release of the drug with the conventional dosage form. The formulation was designed adopting optimization technique, which helps in setting up experiments in such a manner that the information is obtained as efficiently and precisely as possible. Initially, considering buoyancy as the main criteria, blank tablets were compressed for different formulae with various polymers HPMC K 15 M, HPMC K 100 M, Carbopol 934. The tablets were prepared by direct compression method and evaluated for Ranitdine content, in vitro release profile and buoyancy. The dissolution study was carried out in simulated gastric fluid using USP dissolution test apparatus employing paddle stirrer.. This indicates the suitability of the technique chosen for the present dosage form.

Biografía del autor

Ashok Asati completed his M Pharmacy from Singhania University Jhujhunu Rajasthan(India. Ashok Asati having excellent academics record. He is currently working as Asst. Professor at daksh institute of pharmaceutical science chhatarpur (M.P)

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Editorial
LAP LAMBERT Academic Publishing
Año de publicación
2012
Idioma
Inglés
ISBN 10 
3659195677
ISBN 13 
9783659195679
Encuadernación
Tapa blanda
Número de páginas
140
Contacto del fabricante
no disponible
Persona responsable
no disponible