Analysis of Single-Cell Data: ODE Constrained Mixture Modeling and Approximate Bayesian Computation (BestMasters) - Tapa blanda

Libro 26 de 91: BestMasters

Loos, Carolin

 
9783658132330: Analysis of Single-Cell Data: ODE Constrained Mixture Modeling and Approximate Bayesian Computation (BestMasters)

Sinopsis

Carolin Loos introduces two novel approaches for the analysis of single-cell data. Both approaches can be used to study cellular heterogeneity and therefore advance a holistic understanding of biological processes. The first method, ODE constrained mixture modeling, enables the identification of subpopulation structures and sources of variability in single-cell snapshot data. The second method estimates parameters of single-cell time-lapse data using approximate Bayesian computation and is able to exploit the temporal cross-correlation of the data as well as lineage information. 

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Acerca del autor

Carolin Loos is currently doing her PhD at the Institute of Computational Biology at the Helmholtz Zentrum München. She is member of the junior research group „Data-driven Computational Modeling“. 

De la contraportada

Carolin Loos introduces two novel approaches for the analysis of single-cell data. Both approaches can be used to study cellular heterogeneity and therefore advance a holistic understanding of biological processes. The first method, ODE constrained mixture modeling, enables the identification of subpopulation structures and sources of variability in single-cell snapshot data. The second method estimates parameters of single-cell time-lapse data using approximate Bayesian computation and is able to exploit the temporal cross-correlation of the data as well as lineage information.

Contents

  • Modeling and Parameter Estimation for Single-Cell Data
  • ODE Constrained Mixture Modeling for Multivariate Data
  • Approximate Bayesian Computation Using Multivariate Statistics

Target Groups

    Researchers and students in the fields of (bio-)mathematics, statistics, bioinformatics
  • System biologists, biostatisticians, bioinformaticians

The Author
Carolin Loos is currently doing her PhD at the Institute of Computational Biology at the Helmholtz Zentrum München. She is member of the junior research group Data-driven Computational Modeling .


"Sobre este título" puede pertenecer a otra edición de este libro.

Otras ediciones populares con el mismo título

9783658132354: Analysis of Single-Cell Data: ODE Constrained Mixture Modeling and Approximate Bayesian Computation

Edición Destacada

ISBN 10:  3658132353 ISBN 13:  9783658132354
Editorial: Springer Spektrum, 2016
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