Self Eroding Matrix System: A Self Eroding Lipid Based Matrix for an Insoluble Drug - Tapa blanda

Dave, Vivek; Karole, Sarita; Bajaj, Jitendra

 
9783639348088: Self Eroding Matrix System: A Self Eroding Lipid Based Matrix for an Insoluble Drug
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ISBN 10: 3639348087 ISBN 13: 9783639348088
Editorial: VDM Verlag Dr. Müller, 2011

Sinopsis

The aim of this study was to develop a lipid based formulation for a poorly soluble drug belonging to BCS Class II. The intention of the formulation design was to develop a ?self eroding matrix system? made of lipidic excipients which would release the drug mainly by the mechanism of erosion. To attain such as system, lipidic excipients like stearic acid and hydrogenated castor oil were used as matrix formers and surfactants like sodium lauryl sulphate and gelucire 44/14 were used as matrix modifiers. The formulations prepared were subjected to physicochemical and in vitro dissolution and erosion studies.

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Reseña del editor

The aim of this study was to develop a lipid based formulation for a poorly soluble drug belonging to BCS Class II. The intention of the formulation design was to develop a "self eroding matrix system" made of lipidic excipients which would release the drug mainly by the mechanism of erosion. To attain such as system, lipidic excipients like stearic acid and hydrogenated castor oil were used as matrix formers and surfactants like sodium lauryl sulphate and gelucire 44/14 were used as matrix modifiers. The formulations prepared were subjected to physicochemical and in vitro dissolution and erosion studies.

Biografía del autor

Vivek Dave have done M.Pharm in Pharmaceutics from Manipal College of Pharmaceutical Sciences,India. He is Pursuing PhD from Banasthali University, Jaipur, India. His research interest in delivery of various drugs through Transdermal, Nanoparticle & Ocular route.

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Editorial
VDM Verlag Dr. Müller
Año de publicación
2011
Idioma
Inglés
ISBN 10 
3639348087
ISBN 13 
9783639348088
Encuadernación
Tapa blanda
Número de páginas
120
Contacto del fabricante
no disponible
Persona responsable
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