Sinopsis
This is a discussion of the properties that follow from the principles of thermodynamics, aiming to bridge the gap in showing applications of model molecules in modern drug design. The book connects two subjects: drug design - a biological science - and thermodynamics - a physical science. Armed with the knowledge of the three-dimensional structure of a potential binding site of a molecule, the method of structure-based design provides a rapid, rational route to a ligand molecule. Recent developments in the determination of structure and the measurement of thermodynamic parameters of binding have resulted in drawing theoretical and experimental data together to improve ability to model these interactions afresh. The book also outlines future developments in the field of structure-based ligand design.
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Reseña del editor
This book connects two subjects: "drug design" - a biological science - and "thermodynamics" - a physical science. Armed with the knowledge of the three-dimensional structure of a potential binding site of a molecule, the method of structure-based design provides a rapid, rational route to a ligand molecule. Recent developments in the determination of structure and the measurement of thermodynamic parameters of binding have resulted in drawing theoretical and experimental data together to improve our ability to model these interactions de novo. This book presents the state of the art and outlines future developments in the field of structure-based ligand design.
Reseña del editor
This is a discussion of the properties that follow from the principles of thermodynamics, aiming to bridge the gap in showing applications of model molecules in modern drug design. The book connects two subjects: drug design - a biological science - and thermodynamics - a physical science. Armed with the knowledge of the three-dimensional structure of a potential binding site of a molecule, the method of structure-based design provides a rapid, rational route to a ligand molecule. Recent developments in the determination of structure and the measurement of thermodynamic parameters of binding have resulted in drawing theoretical and experimental data together to improve ability to model these interactions afresh. The book also outlines future developments in the field of structure-based ligand design.
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Structure-Based Drug Design: Thermodynamics, Modeling and Strategy (Biotechnology Intelligence Unit)
Librería: Salish Sea Books, Bellingham, WA, Estados Unidos de America
Calificación del vendedor: 5 de 5 estrellas
Hardcover. Condición: Very Good. 3540632506 Very Good; Hardcover; Light wear to covers; Small white label inside back cover; Pages clean & unmarked; Good binding with straight spine; This book will be stored and delivered in a sturdy cardboard box; Blue and gray covers with title in white lettering; 1997, Springer-Verlag Publishing; 188 pages; "Structure-Based Drug Design: Thermodynamics, Modeling and Strategy (Biotechnology Intelligence Unit)," by John E. Ladbury & Patrick R. Connelly. Nº de ref. del artículo: SKU-R7801904235
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