This is a summary of the last ten years' research on Alzheimer's disease. Genetic mutations in the gene with codes for amyloid precursor protein (APP) have now been shown to cause Alzheimer's disease in some families. Other genetic loci are now being discovered which relate to Alzheimer's disease in families. Understanding the normal structure and function of the APP gene product will eventually provide avenues for developing specific therapeutic strategies targeted at the amyloid deposition in the brain. Drugs which can inhibit or dissolve the amyloid, affect the synthesis and proteolysis of APP, or which regulate the activity of the APP gene, are explored in the text.
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This is a summary of the last ten years' research on Alzheimer's disease. Genetic mutations in the gene with codes for amyloid precursor protein (APP) have now been shown to cause Alzheimer's disease in some families. Other genetic loci are now being discovered which relate to Alzheimer's disease in families. Understanding the normal structure and function of the APP gene product will eventually provide avenues for developing specific therapeutic strategies targeted at the amyloid deposition in the brain. Drugs which can inhibit or dissolve the amyloid, affect the synthesis and proteolysis of APP, or which regulate the activity of the APP gene, are explored in the text.
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Couverture rigide. Condición: Bon. Pas de jaquette. Coll. "Research and Perspectives in Alzheimer's Disease". With 55 Figures and 13 Tables. XX + 257 p. Texte en anglais / text in english ! 16x24 cm. 257 p. Reliure éditeur. Bon état. Intérieur en bon état. Sans Jaquette in-8°. Nº de ref. del artículo: L101268
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