The pharmaceutical industry is in a dire situation: R&D still produces no more drugs than 10 years ago, while costs have quadrupled in the meantime. Little advances have been made in innovation efficiency. Worse yet, drug development times are unacceptably long, possible drug development targets are waning, and national healthcare is tightening the cost squeeze. A predictable and efficient pipeline of drug candidates, coupled with a handful of blockbuster drugs, is considered the Holy Grail of pharmaceutical innovation. In this book, the authors develop a case for mastering pharmaceutical innovation focusing on three leading sources of future pharmaceutical competitiveness: new technologies and techniques, better pipeline management, and stronger integration of external innovation. Illustrated with plenty of real-life cases, this book tells you how to put the principles of leading pharmaceutical innovation into practice.
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From the reviews: "This book examines the international pharmaceutical industry with special emphasis on the current and emerging research methodologies a ] . What distinguishes this book from others on the same subject is its emphasis on empirical findings (53 figures, 20 tables) and an exceptionally good, if short, discussion of various research technologies a ] . The six-page glossary of industry terms, when used with its decent index, is a particular joy. a ] recommend this offering to prospective managers and researchers in this industry a ] ." (Robert R. Rothberg, Journal of Product Innovation Management, Vol. 22, 2005)
Pharmaceutical giants have been doubling their investments in drug development, only to see new drug approvals to remain constant for the past decade. This book investigates and highlights a set of proactive strategies. The authors focus on three sources of pharmaceutical innovation: new management methods, new technologies, and new forms of internationalization. Their findings are illustrated in the case of the Swiss pharmaceutical industry, the leading exporter of pharmaceutical products in percentage of GDP, and some of its main pharmaceutical firms such as Novartis and Hoffmann-La Roche.
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