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Sinopsis
A mammalian body consists of more than 200 types of cells; almost all of them having the same genome but different morphology and functions. These differences are due to cell-specific gene regulatory machinery. Mammalian genome has a complex organisation of regulatory sequences associated with different regulatory elements. The linear DNA in the nucleus is folded in a very complex manner and this folding brings distantly placed regions closer to each other. The combination of different DNA binding proteins such as transcription factors and histones; epigenetic marks such as gene position and dynamic modification of DNA and histones; and the three dimensional organisation of regulatory landscape interact in a pervasive and cell specific manner to generate complex spatiotemporal expression patterns. Chromatin Immunoprecipitation (ChIP seq) and Chromosome Conformation Capture (Hi C and 5C) approaches can be integrated with the whole transcriptome shotgun sequencing (RNA-Seq) to decipher Spatial Pattern of binding of regulatory elements to their target genes.
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Reseña del editor
A mammalian body consists of more than 200 types of cells; almost all of them having the same genome but different morphology and functions. These differences are due to cell-specific gene regulatory machinery. Mammalian genome has a complex organisation of regulatory sequences associated with different regulatory elements. The linear DNA in the nucleus is folded in a very complex manner and this folding brings distantly placed regions closer to each other. The combination of different DNA binding proteins such as transcription factors and histones; epigenetic marks such as gene position and dynamic modification of DNA and histones; and the three dimensional organisation of regulatory landscape interact in a pervasive and cell specific manner to generate complex spatiotemporal expression patterns. Chromatin Immunoprecipitation (ChIP seq) and Chromosome Conformation Capture (Hi C and 5C) approaches can be integrated with the whole transcriptome shotgun sequencing (RNA-Seq) to decipher Spatial Pattern of binding of regulatory elements to their target genes.
Biografía del autor
Divya Verma is an Assistant Professor in the Department of Botany at Kalindi College, University of Delhi with an experience of twelve years of teaching. She completed her M.Sc. and Ph.D. in Botany from the MDS University, Ajmer. In 2012, she moved to the University of Edinburgh, U.K. for another Masters in the field of Bioinformatics.
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Spatial Pattern of Transcription Factor Binding Sites in genome
Publicado por
LAP LAMBERT Academic Publishing Jul 2017, 2017
ISBN 10: 3330345845
ISBN 13: 9783330345843
Nuevo
Taschenbuch
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
Calificación del vendedor: 5 de 5 estrellas
Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A mammalian body consists of more than 200 types of cells; almost all of them having the same genome but different morphology and functions. These differences are due to cell-specific gene regulatory machinery. Mammalian genome has a complex organisation of regulatory sequences associated with different regulatory elements. The linear DNA in the nucleus is folded in a very complex manner and this folding brings distantly placed regions closer to each other. The combination of different DNA binding proteins such as transcription factors and histones; epigenetic marks such as gene position and dynamic modification of DNA and histones; and the three dimensional organisation of regulatory landscape interact in a pervasive and cell specific manner to generate complex spatiotemporal expression patterns. Chromatin Immunoprecipitation (ChIP seq) and Chromosome Conformation Capture (Hi C and 5C) approaches can be integrated with the whole transcriptome shotgun sequencing (RNA-Seq) to decipher Spatial Pattern of binding of regulatory elements to their target genes. 60 pp. Englisch. Nº de ref. del artículo: 9783330345843
Cantidad disponible: 2 disponibles
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Spatial Pattern of Transcription Factor Binding Sites in genome
Publicado por
LAP LAMBERT Academic Publishing, 2017
ISBN 10: 3330345845
ISBN 13: 9783330345843
Nuevo
Taschenbuch
Librería: AHA-BUCH GmbH, Einbeck, Alemania
Calificación del vendedor: 5 de 5 estrellas
Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - A mammalian body consists of more than 200 types of cells; almost all of them having the same genome but different morphology and functions. These differences are due to cell-specific gene regulatory machinery. Mammalian genome has a complex organisation of regulatory sequences associated with different regulatory elements. The linear DNA in the nucleus is folded in a very complex manner and this folding brings distantly placed regions closer to each other. The combination of different DNA binding proteins such as transcription factors and histones; epigenetic marks such as gene position and dynamic modification of DNA and histones; and the three dimensional organisation of regulatory landscape interact in a pervasive and cell specific manner to generate complex spatiotemporal expression patterns. Chromatin Immunoprecipitation (ChIP seq) and Chromosome Conformation Capture (Hi C and 5C) approaches can be integrated with the whole transcriptome shotgun sequencing (RNA-Seq) to decipher Spatial Pattern of binding of regulatory elements to their target genes. Nº de ref. del artículo: 9783330345843
Cantidad disponible: 1 disponibles
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Spatial Pattern of Transcription Factor Binding Sites in genome
Publicado por
LAP LAMBERT Academic Publishing, 2017
ISBN 10: 3330345845
ISBN 13: 9783330345843
Nuevo
Tapa blanda
Librería: moluna, Greven, Alemania
Calificación del vendedor: 5 de 5 estrellas
Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Verma DivyaDivya Verma is an Assistant Professor in the Department of Botany at Kalindi College, University of Delhi with an experience of twelve years of teaching. She completed her M.Sc. and Ph.D. in Botany from the MDS University,. Nº de ref. del artículo: 156197863
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Spatial Pattern of Transcription Factor Binding Sites in genome
Publicado por
LAP LAMBERT Academic Publishing, 2017
ISBN 10: 3330345845
ISBN 13: 9783330345843
Nuevo
Paperback
Librería: Revaluation Books, Exeter, Reino Unido
Calificación del vendedor: 5 de 5 estrellas
Paperback. Condición: Brand New. 60 pages. 8.66x5.91x0.14 inches. In Stock. Nº de ref. del artículo: 3330345845
Cantidad disponible: 1 disponibles
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Spatial Pattern of Transcription Factor Binding Sites in genome
Publicado por
LAP LAMBERT Academic Publishing Jul 2017, 2017
ISBN 10: 3330345845
ISBN 13: 9783330345843
Nuevo
Taschenbuch
Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemania
Calificación del vendedor: 5 de 5 estrellas
Taschenbuch. Condición: Neu. Neuware -A mammalian body consists of more than 200 types of cells; almost all of them having the same genome but different morphology and functions. These differences are due to cell-specific gene regulatory machinery. Mammalian genome has a complex organisation of regulatory sequences associated with different regulatory elements. The linear DNA in the nucleus is folded in a very complex manner and this folding brings distantly placed regions closer to each other. The combination of different DNA binding proteins such as transcription factors and histones; epigenetic marks such as gene position and dynamic modification of DNA and histones; and the three dimensional organisation of regulatory landscape interact in a pervasive and cell specific manner to generate complex spatiotemporal expression patterns. Chromatin Immunoprecipitation (ChIP seq) and Chromosome Conformation Capture (Hi C and 5C) approaches can be integrated with the whole transcriptome shotgun sequencing (RNA-Seq) to decipher Spatial Pattern of binding of regulatory elements to their target genes.Books on Demand GmbH, Überseering 33, 22297 Hamburg 60 pp. Englisch. Nº de ref. del artículo: 9783330345843
Cantidad disponible: 2 disponibles