Untranslated Gene Regions and Other Non-coding Elements: Regulation of Eukaryotic Gene Expression (SpringerBriefs in Biochemistry and Molecular Biology) - Tapa blanda

Barrett, Lucy W.

 
9783034806787: Untranslated Gene Regions and Other Non-coding Elements: Regulation of Eukaryotic Gene Expression (SpringerBriefs in Biochemistry and Molecular Biology)
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ISBN 10: 3034806787 ISBN 13: 9783034806787
Editorial: Springer, 2013

Sinopsis

There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as "junk DNA", it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.​

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Reseña del editor

There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.

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Editorial
Springer
Año de publicación
2013
Idioma
Inglés
ISBN 10 
3034806787
ISBN 13 
9783034806787
Encuadernación
Tapa blanda
Número de páginas
64
Contacto del fabricante
no disponible
Persona responsable
CMN Printpool Inh. Mathis Neumann
https://www.also.com/ec/cms5/en_6000/6000/index.jsp

Friedrich-Karl-Str. 9
Hamburg
Alemania

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9783034806800: Untranslated Gene Regions and Other Non-coding Elements: Regulation of Eukaryotic Gene Expression

Edición Destacada

ISBN 10:  3034806809 ISBN 13:  9783034806800
Editorial: Springer, 2013
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