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The Inflammasomes (Progress in Inflammation Research) - Tapa blanda

Libro 1 de 50: Progress in Inflammation Research
 
9783034803434: The Inflammasomes (Progress in Inflammation Research)
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ISBN 10: 3034803435 ISBN 13: 9783034803434
Editorial: Springer, 2013

Sinopsis

The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions of leading international experts in the field, this book provides an extensive overview of the current knowledge of inflammasome biology and their role in health and disease.

"Sinopsis" puede pertenecer a otra edición de este libro.

De la contraportada

The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1? and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions of leading international experts in the field, this book provides an extensive overview of the current knowledge of inflammasome biology and their role in health and disease.

"Sobre este título" puede pertenecer a otra edición de este libro.

Editorial
Springer
Año de publicación
2013
Idioma
Inglés
ISBN 10 
3034803435
ISBN 13 
9783034803434
Encuadernación
Tapa blanda
Número de páginas
240
Editor
Couillin Isabelle, Pétrilli Virginie, Martinon Fabio
Contacto del fabricante
ProductSafety@springernature.com
ProductSafety@springernature.com

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