Cholesterol Modulation of Protein Function: Sterol Specificity and Indirect Mechanisms - Tapa blanda

Sinopsis

Part 1. Sterol specificity in modulating protein function: 1. Chirality effect on cholesterol modulation of protein function.- 2. A critical analysis of molecular mechanisms underlying membrane cholesterol sensitivity of GPCRs.- 3. Regulation of BK channel activity by cholesterol and its derivatives.- 4. Chiral specificity of cholesterol orientation within cholesterol binding sites in inwardly rectifying potassium channels.- Part 2. Indirect modulation of protein function by cholesterol: 5. Cholesterol effect on the physical properties of lipid membranes.- 6. Effect of cholesterol on the dipole potential of lipid membranes.- 7. Mass spectroscopy imaging of cholesterol.- 8. Cholesterol-dependent gating effects on ion channels.

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