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Mitochondria (Cold Spring Harbor Perspectives in Biology) - Tapa blanda

Wallace, Douglas C; Youle, Richard J

 
9781936113354: Mitochondria (Cold Spring Harbor Perspectives in Biology)

Sinopsis

Mitochondria are subcellular organelles that function as "power plants]for the cell, generating energy in the form of ATP from glucose, oxygen, and other molecules. Thought to have arisen about 2 billion years ago when an aerobic bacterium invaded the primitive eukaryotic cell, they have their own DNA, undergo fission and fusion independently, and play an important role in programmed cell death.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology discusses the evolution of mitochondria, their functions in cells, and the numerous diseases in which mitochondrial dysfunction is implicated. The contributors also examine mitochondrial biogenesis, the molecular mechanisms underlying fission and fusion, how proteins are imported from the cytoplasm, and the organization of the mitochondrial DNA.

This book includes chapters covering the involvement of mitochondria in Parkinson’s disease, encephalopathies, tumorigenesis, muscular dystrophy, and other diseases, as well as aging. It is thus a vital reference for all cell and molecular biologists, as well as researchers working on muscle and neurodegenerative diseases, the role of metabolism in aging, and cancer.

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Acerca del autor

Charlotte y Peter Fiell son dos autoridades en historia, teoría y crítica del diseño y han escrito más de sesenta libros sobre la materia, muchos de los cuales se han convertido en éxitos de ventas. También han impartido conferencias y cursos como profesores invitados, han comisariado exposiciones y asesorado a fabricantes, museos, salas de subastas y grandes coleccionistas privados de todo el mundo. Los Fiell han escrito numerosos libros para TASCHEN, entre los que se incluyen 1000 Chairs, Diseño del siglo XX, El diseño industrial de la A a la Z, Scandinavian Design y Diseño del siglo XXI.

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