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Proton Pump Inhibitors (PPIs): Prevalence of Use, Effectiveness & Implications for Clinicians (Pharmacology-Research, Safety Testing and Regulation) - Tapa dura

 
9781634828901: Proton Pump Inhibitors (PPIs): Prevalence of Use, Effectiveness & Implications for Clinicians (Pharmacology-Research, Safety Testing and Regulation)

Sinopsis

Proton pump inhibitors (PPIs) have become a mainstay of therapy not only in the practice of gastroenterology, but also for general medicine and even for the general public. Recently, proton pump inhibitors have been associated with a number of potential complications including impaired vitamin and mineral absorption, altered drug metabolism and increased risk for infections. The outline for the basis for these reported risks are examined in this book, the current clinical evidence is discussed, and the authors offer insight into the likely clinical significance of each complication. Furthermore, the pathophysiology of acid secretion and inhibition, with a specific focus on the pharmacological principles surrounding the use of PPIs are reviewed. Relevant information on the management of acid-related disordered is provided for clinicians. Other chapters explore the current literature on potential complications associated with long-term PPI use, the benefits and risks of routine use of proton pump inhibitors in the intensive care unit (ICU), often associated with adverse events such as a significantly increased risk of infectious complications, and the use and misuse of proton pump inhibitors in the general population.

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Acerca del autor

Charlotte y Peter Fiell son dos autoridades en historia, teoría y crítica del diseño y han escrito más de sesenta libros sobre la materia, muchos de los cuales se han convertido en éxitos de ventas. También han impartido conferencias y cursos como profesores invitados, han comisariado exposiciones y asesorado a fabricantes, museos, salas de subastas y grandes coleccionistas privados de todo el mundo. Los Fiell han escrito numerosos libros para TASCHEN, entre los que se incluyen 1000 Chairs, Diseño del siglo XX, El diseño industrial de la A a la Z, Scandinavian Design y Diseño del siglo XXI.

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