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Cytokines: From Basic Mechanisms of Cellular Control to New Therapeutics (Cold Spring Harbor Perspectives in Biology) - Tapa blanda

Schreiber, Robert; Leonard, Warren J

 
9781621821250: Cytokines: From Basic Mechanisms of Cellular Control to New Therapeutics (Cold Spring Harbor Perspectives in Biology)
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ISBN 10: 1621821250 ISBN 13: 9781621821250
Editorial: Cold Spring Harbor Laboratory Press, 2018

Sinopsis

Cytokines (e.g., interleukins and interferons) are small signaling proteins that are essential for communication between cells. They are important regulators of the immune system, helping to control lymphocyte development and function, orchestrate inflammation, and defeat microbial and viral invaders. But they also play important roles in the nervous system, embryonic development, and diseases such as cancer.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology covers the spectrum of cytokines that are produced and their roles in normal physiology and disease. The contributors examine the numerous cytokines and their cognate receptors, the downstream signaling mechanisms (e.g., JAK-STAT pathways) that mediate the effects of cytokines on cells, and the regulators that keep them in check (e.g., long noncoding RNAs and the SOCS and IRF protein families). These molecular interactions are discussed in the context of their physiological effects; the roles of cytokines in the development and activities of the immune system are emphasized.

The authors also explore how the actions of cytokines may be modulated for treating patients with autoimmune disorders, immunodeficiency, infections, allergies, and cancer. Thus, this volume is an indispensable reference not only for cell biologists and immunologists but for all who are interested in targeting cytokine signaling for therapeutic purposes.

"Sinopsis" puede pertenecer a otra edición de este libro.

Acerca del autor

Charlotte y Peter Fiell son dos autoridades en historia, teoría y crítica del diseño y han escrito más de sesenta libros sobre la materia, muchos de los cuales se han convertido en éxitos de ventas. También han impartido conferencias y cursos como profesores invitados, han comisariado exposiciones y asesorado a fabricantes, museos, salas de subastas y grandes coleccionistas privados de todo el mundo. Los Fiell han escrito numerosos libros para TASCHEN, entre los que se incluyen 1000 Chairs, Diseño del siglo XX, El diseño industrial de la A a la Z, Scandinavian Design y Diseño del siglo XXI.

"Sobre este título" puede pertenecer a otra edición de este libro.

Editorial
Cold Spring Harbor Laboratory Press
Año de publicación
2018
Idioma
Inglés
ISBN 10 
1621821250
ISBN 13 
9781621821250
Encuadernación
Tapa blanda
Número de edición
1
Número de páginas
480
Contacto del fabricante
no disponible
Persona responsable
no disponible