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Calcium Signaling (Protein Biochemistry, Synthesis, Structure and Cellular Functions) - Tapa dura

 
9781613243138: Calcium Signaling (Protein Biochemistry, Synthesis, Structure and Cellular Functions)
Tapa dura
ISBN 10: 1613243138 ISBN 13: 9781613243138
Editorial: Nova Science Publishers Inc, 2012

Sinopsis

Signal transduction plays a pivotal role in cellular regulation. The second messenger is generated in cells once the first messenger binds to the receptors of plasma membranes. The second messenger, which was found firstly, is cyclic adenosine monophosphate. After that, intracellular calcium ion (Ca2+) has been demonstrated to play a role as a second messenger for hormonal stimulation in cells. The pivotal role of Ca2+ in cellular regulation was established with the finding of calmodulin and protein kinase C that modulate the effect of Ca2+ in the regulation of cellular functions. Calcium signalling is probably the most ubiquitous cellular signal that mediates the action of many hormones, cytokines, and neurotransmitters. This book provides an in depth examination of calcium signalling.

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Acerca del autor

Masayoshi Yamaguchi, Ph.D., IOM, FAOE, DDG, DG, is Adjunct Professor, Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA (2013 - ). Dr. Yamaguchi is engaged in the fields of endocrinology and cell signaling since 1971, and these researches are developed in the aspect of biochemistry, molecular biology, endocrinology, metabolism, nutrition, pharmacology, and toxicology. Dr Yamaguchi has an interesting for cell signaling mechanism, bone biology, nutritional factor and osteoporosis prevention, diabetes and diabetic osteoporosis, cancer biology, and cancer cell bone metastasis. Dr. Yamaguchi discovered two novel proteins and genes; cell signaling suppressor protein (named regucalcin; 1978) and transcriptional factor RGPR-p117 (regucalcin gene promoter region-related protein; 2001). Dr Yamaguchi generated regucalcin transgenic rats, which were registered as international patents including USA, EU and Japan, and this animal was found to induce osteoporosis and hyperlipidemia. Moreover, Dr. Yamaguchi proposed the potential role of regucalcin as a key suppressor protein in carcinogenesis. Thus far, Dr Yamaguchi published over 550 English articles to professional journals with peer-review, and registered over 20 national and international patents.

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Editorial
Nova Science Publishers Inc
Año de publicación
2012
Idioma
Inglés
ISBN 10 
1613243138
ISBN 13 
9781613243138
Encuadernación
Tapa dura
Número de páginas
244
Editor
Yamaguchi Ph.D. IOM FAOE DDG DG Masayoshi
Contacto del fabricante
no disponible
Persona responsable
Buchpark GmbH
gpsr@buchpark.de

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