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High Content Screening: A Powerful Approach to Systems Cell Biology And Drug Discovery: 356 (Methods in Molecular Biology, 356) - Tapa dura

 
9781588297310: High Content Screening: A Powerful Approach to Systems Cell Biology And Drug Discovery: 356 (Methods in Molecular Biology, 356)
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ISBN 10: 1588297314 ISBN 13: 9781588297310
Editorial: Humana Press, 2006

Sinopsis

There has always been some tension between proponents of hypothesis-driven and discovery-driven research in the broad field of life sciences. Academic research has been primarily focused on hypothesis-driven research. However, the success of the human genome project, a discovery-driven research approach, has opened the door to adding other types of discovery-driven research to a continuum of research approaches. In contrast, drug discovery research in the pharmaceutical industry has embraced discovery-driven research for many years. A good example has been the discovery of active compounds from large chemical libraries, through screening campaigns. The success of the human genome project has also demonstrated the need for both academic researchers and industrial researchers to now understand the functions of genes and gene products. The cell is the basic unit of life and it has been at the cellular level where function can be demonstrated most cost-effectively and rapidly. High content screening (HCS) was developed by Cellomics Inc. in the mid-1990s to address the need for a platform that could be used in the discovery-driven research and development required to understand the functions of genes and gene products at the level of the cell.

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De la contraportada

High content screening (HCS) was developed by Cellomics Inc. in the mid-1990s to address the need for a platform that could be used in the discovery-driven research and development required to understand the functions of genes and gene products at the level of the cell. High Content Screening: A Powerful Approach to Systems Cell Biology and Drug Discovery discusses its use as a high throughput platform to understand the functions of genes, RNA, proteins, and other cellular constituents at the level of the living cell.
High Content Screening is assembled to assist both existing users of HCS, as well as investigators considering the addition of a discovery-driven platform to their research and development activities. The chapters have been organized into sections that highlight the importance of integrating instrumentation, application software, reagents, and informatics. In addition, there is a combination of pure review chapters on key topics and specific methods chapters.

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Editorial
Humana Press
Año de publicación
2006
Idioma
Inglés
ISBN 10 
1588297314
ISBN 13 
9781588297310
Encuadernación
Tapa dura
Número de edición
1
Número de páginas
464
Editor
Taylor D. Lansing
Contacto del fabricante
Springer-Verlag GmbH
customerservice@springernature.com

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