Methods in Membrane Lipids presents a compendium of methodologies for the study of membrane lipids, varying from traditional lab bench experimentation to computer simulation and theoretical models. This volume provides a comprehensive set of techniques for studying membrane lipids, and their interactions with other membrane lipids, with membrane proteins, and with exogenous agents such as anesthetics. The progression of chapters increases in complexity, initially presenting introductory concepts and methods for the study of simple structures and interactions, then moving to the study of more complex structures and interactions, including: behaviors of lipids in water systems and phases; membrane lipid movements and diffusion; properties of lipids in mono and bilayers; complex lipid domains; and membrane-lipid interaction with proteins and drugs. Each chapter is written by an internationally recognized expert in the field.
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From the reviews:
"A compilation of protocols that addresses the ... analysis of membrane lipid structure to polymorphism, lipid domains and (macro-) molecular interactions. It is a timely addition to the series on a topic that begs attention. It is a valuable reference material for researchers in lipidology and practitioners whose work involves understanding membrane structure and function. ... a valuable compilation of biophysical methodologies employed in the study of membrane lipids that will no doubt be useful to anyone with an interest in membrane structure and function." (Dr Seetharaman Vaidyanathan, Molecular Biotechnology, March, 2008)
"The book deals with the membrane models and biophysical approaches used to study them. It is a compendium of various experimental and theoretical methods for investigating lipids, lipid aggregates, and, to some extent, membrane proteins. ... The book is not only a collection of methods, but a textbook that can be recommended for scientists and students with a deeper interest in lipid biochemistry and biophysics. ... it can be highly recommended." (Thomas Kolter, ChemBioChem, Issue 9, 2008)
This book presents a compendium of methodologies for the study of membrane lipids, varying from traditional lab bench experimentation to computer simulation and theoretical models. The volume provides a comprehensive set of techniques for studying membrane lipids with a strong biophysical emphasis. It compares the various available techniques including the pros and cons as seen by the experts.
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