Combination Cancer Therapy: Modulators and Potentiators (Cancer Drug Discovery and Development) - Tapa dura

Libro 34 de 96: Cancer Drug Discovery and Development
 
9781588292001: Combination Cancer Therapy: Modulators and Potentiators (Cancer Drug Discovery and Development)
Tapa dura
ISBN 10: 1588292002 ISBN 13: 9781588292001
Editorial: Humana Press, 2004

Sinopsis

Expert physician-scientists and clinicians review those combinations of novel target agents classic chemotherapies that hold the most promise for the future of medical oncology, and detail their optimal sequence, pharmacokinetic interactions, and interaction with downstream cellular signals. The combinations run the gamut of targeted therapies against cell surface receptors (EGF-R and HER2), the cell cycle (the CDKs), signal transduction events (PKC and NF-kB), apoptosis (bcl-2), as well as focused therapies in ovarian cancer, hematologic diseases, and breast cancer. The authors emphasize novel translational approaches that are rapidly moving from the laboratory bench top to the patient’s bedside for the future treatments in cancer therapy.

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De la contraportada

Early clinical trials of the new molecular-based anticancer agents have shown that many are marginal in controlling cancer, but prove to be potent modulators and potentiators of chemotherapy-induced apoptosis when used in combination with classic cytotoxic drugs or radiation. In Combination Cancer Therapy: Modulators and Potentiators, expert physician-scientists and clinicians with first-hand experience in the clinical development of targeted therapies review those combinations that hold the most promise for the future of medical oncology, detailing their optimal sequence, pharmacokinetic interactions, and interaction with downstream cellular signals. The combinations run the gamut of targeted therapies against cell surface receptors (EGF-R and HER2), the cell cycle (the CDKs), signal transduction events (PKC and NF-kB), apoptosis (bcl-2), as well as focused therapies in ovarian cancer, hematologic diseases, and breast cancer. The authors emphasize novel translational approaches that are rapidly moving from the laboratory benchtop to the patient's bedside as a new generation of cancer therapeutics.
Cutting-edge and forward-looking, Combination Cancer Therapy: Modulators and Potentiators offers everyone in the fields of cancer drug development and therapy a powerful new understanding of the optimal sequencing and scheduling of new combination drug therapies necessary to maximize the effects for cancer patients today.

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Editorial
Humana Press
Año de publicación
2004
Idioma
Inglés
ISBN 10 
1588292002
ISBN 13 
9781588292001
Encuadernación
Tapa dura
Número de páginas
296
Editor
Schwartz Gary K.
Contacto del fabricante
no disponible
Persona responsable
no disponible

Otras ediciones populares con el mismo título

9781627038065: Combination Cancer Therapy: Modulators and Potentiators (Cancer Drug Discovery and Development)

Edición Destacada

ISBN 10:  162703806X ISBN 13:  9781627038065
Editorial: Humana, 2014
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