PTEN: Methods and Protocols: 1388 (Methods in Molecular Biology, 1388) - Tapa dura

 
9781493932979: PTEN: Methods and Protocols: 1388 (Methods in Molecular Biology, 1388)
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ISBN 10: 1493932977 ISBN 13: 9781493932979
Editorial: Humana, 2015

Sinopsis

This volume provides detailed descriptions of prevailing and novel techniques used by experts in the study of PTEN function in disease and biology. The book begins with chapters exploring methods to detect expression levels of PTEN in normal and diseased human specimens; methods to evaluate specific PTEN function in brain cancer; methods that utilize a new biosensor to measure PTEN regulation; and techniques to measure post-transcriptional regulation of PTEN by micoRNAs and ceRNAs. Other chapters present methods describing novel techniques to detect PTEN localization and previously unstudied structural features of PTEN measured through X-Ray Crystallography and Hydrogen Deuterium Exchange Mass Spectrometry. The book concludes with methods to study PTEN function in model organisms including mice and C. elegans. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and thorough, PTEN: Methods and Protocols is a valuable collection of methodologies and protocols useful to researchers who are interested in the PTEN field.

"Sinopsis" puede pertenecer a otra edición de este libro.

Acerca del autor

Leonardo Salmena Ph.D. Assistant Scientist Ontario Cancer Institute/University Health Network Princess Margaret Hospital 9-412 610 University Avenue Toronto, Ontario M5G 2M9 E: salmenal@uhnres.utoronto.ca P: 416-946-4501 Ext. 3695 Vuk Stambolic, PhD Senior Scientist Ontario Cancer Institute (OCI) Primary Office Princess Margaret Cancer Centre 10th Floor Rm 10-123 610 University Ave Toronto, Ontario Canada M5G 2M9

De la contraportada

This volume provides detailed descriptions of prevailing and novel techniques used by experts in the study of PTEN function in disease and biology. The book begins with chapters exploring methods to detect expression levels of PTEN in normal and diseased human specimens; methods to evaluate specific PTEN function in brain cancer; methods that utilize a new biosensor to measure PTEN regulation; and techniques to measure post-transcriptional regulation of PTEN by micoRNAs and ceRNAs. Other chapters present methods describing novel techniques to detect PTEN localization and previously unstudied structural features of PTEN measured through X-Ray Crystallography and Hydrogen Deuterium Exchange Mass Spectrometry. The book concludes with methods to study PTEN function in model organisms including mice and C. elegans. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and thorough, PTEN: Methods and Protocols is a valuable collection of methodologies and protocols useful to researchers who are interested in the PTEN field.

"Sobre este título" puede pertenecer a otra edición de este libro.

Editorial
Humana
Año de publicación
2015
Idioma
Inglés
ISBN 10 
1493932977
ISBN 13 
9781493932979
Encuadernación
Tapa dura
Número de edición
1
Número de páginas
338
Editor
Salmena Leonardo, Stambolic Vuk
Contacto del fabricante
Springer-Verlag GmbH
customerservice@springernature.com

Tiergartenstraße 17
Heidelberg
Baden-Württemberg
69121
Alemania

Otras ediciones populares con el mismo título

9781493980154: PTEN: Methods and Protocols: 1388 (Methods in Molecular Biology)

Edición Destacada

ISBN 10:  1493980157 ISBN 13:  9781493980154
Editorial: Humana, 2019
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