Assessing Rare Variation in Complex Traits: Design and Analysis of Genetic Studies - Tapa dura

 
9781493928231: Assessing Rare Variation in Complex Traits: Design and Analysis of Genetic Studies
Tapa dura
ISBN 10: 1493928236 ISBN 13: 9781493928231
Editorial: Springer, 2015

Sinopsis

Assessing Rare Variation in Complex Traits

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De la contraportada

This unique volume is the first to cover a wide range of design and analysis issues in genetic studies of rare variants, with contributions from experts in the field, through large-scale international consortia including the UK10K Project, GO-T2D and T2D-GENES. The book presents state-of-the-art methodology for rare variant detection and calling, imputation, and analysis in samples of unrelated individuals and families. It also covers analytical issues associated with the study of rare variants, such as the impact of fine-scale population structure, and rare variants studies in a meta-analysis framework.

This book covers multiple aspects of study design, analysis and interpretation for complex trait studies focusing on rare sequence variation. In many areas of genomic research, including complex trait association studies, technology is in danger of outstripping our capacity to analyze and interpret the vast amounts of data generated.

The field of statistical genetics in the whole-genome sequencing era is still in its infancy, but as this book illustrates, powerful methods to analyze the aggregation of low-frequency and rare variants are now starting to emerge.

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Editorial
Springer
Año de publicación
2015
Idioma
Inglés
ISBN 10 
1493928236
ISBN 13 
9781493928231
Encuadernación
Tapa dura
Número de edición
1
Número de páginas
276
Editor
Zeggini Eleftheria, Morris Ph.D. Andrew
Contacto del fabricante
Springer-Verlag GmbH
customerservice@springernature.com

Tiergartenstraße 17
Heidelberg
Baden-Württemberg
69121
Alemania

Otras ediciones populares con el mismo título

9781493945184: Assessing Rare Variation in Complex Traits: Design and Analysis of Genetic Studies

Edición Destacada

ISBN 10:  1493945181 ISBN 13:  9781493945184
Editorial: Springer, 2016
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